Rhodamine B

Modify Date: 2025-08-20 19:27:30

Rhodamine B structure	Common Name	Rhodamine B
	CAS Number	81-88-9	Molecular Weight	479.010
	Density	0.79 g/mL at 20 °C	Boiling Point	N/A
	Molecular Formula	C₂₈H₃₁ClN₂O₃	Melting Point	210-211 (dec.)(lit.)
	MSDS	Chinese USA	Flash Point	12 °C
	Symbol	GHS05, GHS07	Signal Word	Danger

Use of Rhodamine B

Rhodamine B is a staining fluorescent dye, commonly used for dyeing textiles, paper, soap, leather, and drugs.

Name	rhodamine B
Synonym	More Synonyms

Description	Rhodamine B is a staining fluorescent dye, commonly used for dyeing textiles, paper, soap, leather, and drugs.
Related Catalog	Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others
In Vitro	Rhodamine B induces a concentration-dependent reduction of root meristem cells of A. cepa. mitotic activity. Rhodamine B induces various nuclear aberrations in A. cepa. root cells. In the 100 and 200 ppm rhodamine B groups, the frequencies of NBUDs and BN surpass those of the positive control (MMS) group. Rhodamine B-induced changes of H2O2 (a) and MDA (b) level increase in a concentration-dependent manner in A. cepa. roots[1].
References	[1]. Tan D, et al. Rhodamine B induces long nucleoplasmic bridges and other nuclear anomalies in Allium cepa root tip cells. Environ Sci Pollut Res Int. 2014 Mar;21(5):3363-70.

Density	0.79 g/mL at 20 °C
Melting Point	210-211 (dec.)(lit.)
Molecular Formula	C₂₈H₃₁ClN₂O₃
Molecular Weight	479.010
Flash Point	12 °C
Exact Mass	478.202332
PSA	56.69000
LogP	2.56500
Storage condition	Store at RT.
Water Solubility	SOLUBLE

Rhodamine B MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BP3675000

CHEMICAL NAME :: Ammonium, (9-(o-carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-yl idene)diethyl-, chloride

CAS REGISTRY NUMBER :: 81-88-9

LAST UPDATED :: 199710

DATA ITEMS CITED :: 29

MOLECULAR FORMULA :: C28-H31-N2-O3.Cl

MOLECULAR WEIGHT :: 479.06

WISWESSER LINE NOTATION :: T C666 BO EYJ EUK2&2 IR BVQ& MN2&2 &Q &G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 112 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 89 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 887 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 144 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 50400 mg/kg/12W-C

TOXIC EFFECTS :: Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 110 mg/kg/13W-I

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3600 mg/kg/68W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Blood - lymphoma, including Hodgkin's disease Tumorigenic - tumors at site of application

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3870 mg/kg/68W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 60 mg/kg

SEX/DURATION :: female 7-10 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: Sex chromosome loss and nondisjunction

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Mammal - species unspecified Fibroblast

DOSE/DURATION :: 2 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 88,211,1981 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,221,1978 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,221,1978 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84376 No. of Facilities: 3759 (estimated) No. of Industries: 38 No. of Occupations: 37 No. of Employees: 40674 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84376 No. of Facilities: 12726 (estimated) No. of Industries: 91 No. of Occupations: 88 No. of Employees: 198323 (estimated) No. of Female Employees: 75440 (estimated)

Symbol	GHS05, GHS07
Signal Word	Danger
Hazard Statements	H302-H318-H412
Precautionary Statements	P273-P280-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful
Risk Phrases	R22;R41;R68
Safety Phrases	S7-S16-S24/25-S26-S36/37/39-S39
RIDADR	UN 1219 3/PG 2
WGK Germany	2
RTECS	BP3675000
Hazard Class	3.0
HS Code	32041300

3,6-bis(diethyl...

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Rhodamine B

CAS#:81-88-9

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Rhodamine B hyd...

CAS#:74317-53-6

Rhodamine B

CAS#:81-88-9

Literature: Dyes and Pigments, , vol. 98, # 3 p. 339 - 346

N/A

CAS#:1167601-09-3

Rhodamine B

CAS#:81-88-9

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 10 p. 2916 - 2919

Precursor 1
CAS#:74317-53-6 Rhodamine B hyd...
DownStream 8
CAS#:39393-39-0 crystal violet CAS#:509-34-2 Solvent Red 49 CAS#:103-82-2 Phenylacetic acid CAS#:79-14-1 Glycolic acid
CAS#:849585-22-4 2-hydroxypropio... CAS#:57-55-6 Propylene Glycol CAS#:626-89-1 4-Methyl-1-pentanol CAS#:100-21-0 Terephthalic acid

HS Code	2922299090
Summary	2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

The dynamics of giant unilamellar vesicle oxidation probed by morphological transitions.

Biochim. Biophys. Acta 1838(10) , 2615-24, (2014)

We have studied the dynamics of Lissamine Rhodamine B dye sensitization-induced oxidation of 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) giant unilamellar vesicles (GUVs), where the progression of...

Graphene oxide - gelatin nanohybrids as functional tools for enhanced Carboplatin activity in neuroblastoma cells.

Pharm. Res. 32 , 2132-43, (2015)

Preparation of Nanographene oxide (NGO) - Gelatin hybrids for efficient treatment of Neuroblastoma.Nanohybrids were prepared via non-covalent interactions. Spectroscopic tools have been used to discri...

Facile room-temperature synthesis of carboxylated graphene oxide-copper sulfide nanocomposite with high photodegradation and disinfection activities under solar light irradiation.

Sci. Rep. 5 , 16369, (2015)

Carboxylic acid functionalized graphene oxide-copper (II) sulfide nanoparticle composite (GO-COOH-CuS) was prepared from carboxylated graphene oxide and copper precursor in dimethyl sulfoxide (DMSO) b...

Basic Violet 10

redno213

D and C Red No. 19

c.i.749

9-(2-carboxyphenyl)-3,6-bis(diethylamino)xanthylium chloride

MFCD00011931

AKA214

rhodamine blue

AKA213

Pilot578

EINECS 201-383-9

Rhodamine B

rhodamine hydrochloride

C.I. Basic Violet 10

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Rhodamine B
Price: Check
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BioBioPha
China
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Rhodamine B
Price: ￥198.0/20mg ￥255.0/5g ￥925.0/25g
Purity: 98.0%
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DC Chemicals Limited
China
Product Name: Rhodamine B
Price: $280.0/20mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Rhodamine B
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Rhodamine B
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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Price: ￥108/100g

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Rhodamine B

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Rhodamine B Biological Activity

Chemical & Physical Properties

MSDS

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CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

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