3-Iodo-4-methylbenzoic acid

Modify Date: 2024-01-06 17:55:18

3-Iodo-4-methylbenzoic acid Structure
3-Iodo-4-methylbenzoic acid structure
Common Name 3-Iodo-4-methylbenzoic acid
CAS Number 82998-57-0 Molecular Weight 262.044
Density 1.9±0.1 g/cm3 Boiling Point 355.2±30.0 °C at 760 mmHg
Molecular Formula C8H7IO2 Melting Point 210-212 °C(lit.)
MSDS Chinese USA Flash Point 168.6±24.6 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 3-Iodo-4-methylbenzoic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.9±0.1 g/cm3
Boiling Point 355.2±30.0 °C at 760 mmHg
Melting Point 210-212 °C(lit.)
Molecular Formula C8H7IO2
Molecular Weight 262.044
Flash Point 168.6±24.6 °C
Exact Mass 261.949066
PSA 37.30000
LogP 3.57
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.646

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S37/39-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2916399090

 Synthetic Route

~96%

3-Iodo-4-methylbenzoic acid Structure

3-Iodo-4-methyl...

CAS#:82998-57-0

Literature: BRISTOL-MYERS SQUIBB COMPANY; PRACITTO, Richard; KADOW, John, F.; BENDER, John, A.; BENO, Brett, R.; GRANT-YOUNG, Katharine; HAN, Ying; HEWAWASAM, Piyasena; NICKEL, Andrew; PARCELLA, Kyle, E.; YEUNG, Kap-Sun; CHUPAK, Louis, S. Patent: WO2011/112186 A1, 2011 ; Location in patent: Page/Page column 196 ; WO 2011/112186 A1

~92%

3-Iodo-4-methylbenzoic acid Structure

3-Iodo-4-methyl...

CAS#:82998-57-0

Literature: Azarifar, Davood; Khosravi, Kaveh; Najminejad, Zohreh; Soleimani, Khadijeh Journal of the Iranian Chemical Society, 2012 , vol. 9, # 3 p. 321 - 326

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3-Iodo-4-methylbenzoic acid Structure

3-Iodo-4-methyl...

CAS#:82998-57-0

Literature: Journal of the Chemical Society, , vol. 103, p. 236

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3-Iodo-4-methylbenzoic acid Structure

3-Iodo-4-methyl...

CAS#:82998-57-0

Literature: Chemische Berichte, , vol. 26, p. 1733

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3-Iodo-4-methylbenzoic acid Structure

3-Iodo-4-methyl...

CAS#:82998-57-0

Literature: Journal of Heterocyclic Chemistry, , vol. 23, # 5 p. 1333 - 1337

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3-Iodo-4-methylbenzoic acid Structure

3-Iodo-4-methyl...

CAS#:82998-57-0

Literature: Chemische Berichte, , vol. 26, p. 1733

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3-Iodo-4-methylbenzoic acid Structure

3-Iodo-4-methyl...

CAS#:82998-57-0

Literature: Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2940 - 2948

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Detail
Literature: Journal of the Indian Chemical Society, , vol. 7, p. 503

 Customs

HS Code 2916399090
Summary 2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles2

More Articles
A polar substituent-containing acylation agent for the radioiodination of internalizing monoclonal antibodies: N-succinimidyl 4-guanidinomethyl-3-[131I]iodobenzoate ([131I]SGMIB).

Bioconjug. Chem. 12(3) , 428-38, (2001)

The objective of this study was to develop an acylation agent for the radioiodination of monoclonal antibodies that would maximize retention of the label in tumor cells following receptor- or antigen-...

Synthesis of N-succinimidyl 4-guanidinomethyl-3-[*I]iodobenzoate: a radio-iodination agent for labeling internalizing proteins and peptides.

Nat. Protoc. 2(2) , 282-6, (2007)

This protocol describes a detailed procedure for the synthesis of N-succinimidyl 4-guanidinomethyl-3-[*I]iodobenzoate ([*I]SGMIB), an agent useful in the radio-iodination of proteins, including monocl...

 Synonyms

Benzoic acid,3-iodo-4-methyl
3-Iodo-4-methylbenzoic acid
MFCD00010392
3-iodo-4-methyl benzoic acid
4-methyl-3-iodobenzoic acid
3-Iodo-p-toluic Acid
3-iodo-4-toluic acid
3-iodotoluic acid
Benzoic acid, 3-iodo-4-methyl-