3-Iodo-4-methylbenzoic acid
3-Iodo-4-methylbenzoic acid structure
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Common Name | 3-Iodo-4-methylbenzoic acid | ||
|---|---|---|---|---|
| CAS Number | 82998-57-0 | Molecular Weight | 262.044 | |
| Density | 1.9±0.1 g/cm3 | Boiling Point | 355.2±30.0 °C at 760 mmHg | |
| Molecular Formula | C8H7IO2 | Melting Point | 210-212 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 168.6±24.6 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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A polar substituent-containing acylation agent for the radioiodination of internalizing monoclonal antibodies: N-succinimidyl 4-guanidinomethyl-3-[131I]iodobenzoate ([131I]SGMIB).
Bioconjug. Chem. 12(3) , 428-38, (2001) The objective of this study was to develop an acylation agent for the radioiodination of monoclonal antibodies that would maximize retention of the label in tumor cells following receptor- or antigen-mediated internalization. The strategy taken was to add a p... |
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Synthesis of N-succinimidyl 4-guanidinomethyl-3-[*I]iodobenzoate: a radio-iodination agent for labeling internalizing proteins and peptides.
Nat. Protoc. 2(2) , 282-6, (2007) This protocol describes a detailed procedure for the synthesis of N-succinimidyl 4-guanidinomethyl-3-[*I]iodobenzoate ([*I]SGMIB), an agent useful in the radio-iodination of proteins, including monoclonal Abs, and peptides that undergo internalization after r... |
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