Boc-C16-COOH
Modify Date: 2024-01-04 10:25:58
Boc-C16-COOH structure
|
Common Name | Boc-C16-COOH | ||
|---|---|---|---|---|
| CAS Number | 843666-40-0 | Molecular Weight | 370.56600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H42O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Boc-C16-COOHBoc-C16-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-C16-COOH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1] |
| Name | 18-[(2-methylpropan-2-yl)oxy]-18-oxooctadecanoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Boc-C16-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-C16-COOH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1] |
|---|---|
| Related Catalog | |
| Target |
Non-cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Molecular Formula | C22H42O4 |
|---|---|
| Molecular Weight | 370.56600 |
| Exact Mass | 370.30800 |
| PSA | 63.60000 |
| LogP | 6.65430 |
| Hazard Codes | Xn |
|---|---|
| HS Code | 2918990090 |
|
~%
Boc-C16-COOH CAS#:843666-40-0 |
| Literature: Novo Nordisk A/S Patent: US2011/306551 A1, 2011 ; |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
| HS Code | 2918990090 |
|---|---|
| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
| Octadecanedioicacid,mono(1,1-dimethylethyl) ester (9CI) |
| Octadecanedioic acid,1-(1,1-dimethylethyl) ester |
| Octadecanedioic acid mono-tert-butyl ester |
| 18-tert-butoxy-18-oxooctadecanoic acid |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Boc-C16-COOH
- Price: Click To Check
- Purity: 97.0%
- Delivery: 10 Day
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- Chengdu Pukang Biotechnology Co., Ltd.
- China
- Product Name: Boc-C16-COOH
- Price: ￥Inquiry/10g
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- DC Chemicals Limited
- China
- Product Name: Boc-C16-COOH
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- Nanjing Peptide Biotech Ltd
- China
- Product Name: Octadecanedioic acid mono-tert-butyl ester
- Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
- Purity: 98.0%
- Delivery: 7 Day
- Contact: jom
- Email: chenglong.fan@njpeptide.com
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: TIANFUCHEM--843666-40-0---C22H42O4
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Delivery: Inquiry
- Contact: Anson
- Email: info@tianfuchem.com
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