ZK-90055 (hydrochloride) structure
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Common Name | ZK-90055 (hydrochloride) | ||
|---|---|---|---|---|
| CAS Number | 84638-81-3 | Molecular Weight | 342.81800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H23ClN2O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ZK-90055 (hydrochloride)ZK-90055 hydrochloride is a β2 adrenergic receptor agonist. |
| Name | methyl 4-[2-(tert-butylamino)-1-hydroxyethyl]-7-hydroxy-1H-indole-2-carboxylate,hydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | ZK-90055 hydrochloride is a β2 adrenergic receptor agonist. |
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| Related Catalog | |
| Target |
β2 adrenergic receptor[1] |
| In Vivo | Contrasting a pro-drug, a soft-drug is active per se when given locally but is rapidly inactivated when it reaches the general circulation. Thus, a long duration of action at a minimum of systemic side effects may be achieved after inhalation of a h2-agonist designed in this way. One such example is ZK-90055, an indol derivative with a hydrolysable ester bond on the ring system. The development of ZK-90055 is stopped before clinical trials are commenced[2]. |
| References |
| Molecular Formula | C16H23ClN2O4 |
|---|---|
| Molecular Weight | 342.81800 |
| Exact Mass | 342.13500 |
| PSA | 94.58000 |
| LogP | 3.27450 |
| Storage condition | 2-8℃ |
| ZK-90055 (hydrochloride) |