YM-53403

Modify Date: 2024-02-20 17:34:00

YM-53403 Structure
YM-53403 structure
Common Name YM-53403
CAS Number 851331-05-0 Molecular Weight 583.699
Density 1.4±0.1 g/cm3 Boiling Point 787.9±60.0 °C at 760 mmHg
Molecular Formula C36H29N3O3S Melting Point N/A
MSDS N/A Flash Point 430.3±32.9 °C

 Use of YM-53403


YM-53403 (YM53403) is a specific anti-respiratory syncytial virus (RSV) agent with EC50 of 0.2 uM in plaque reduction assays; displays 100-fold more potent than ribavirin, an attractive compound for the treatment of RSV infection.

 Names

Name 6-{4-[(2-Biphenylylcarbonyl)amino]benzoyl}-N-cyclopropyl-5,6-dihydro-4H-thieno[3,2-d][1]benzazepine-2-carboxamide
Synonym More Synonyms

 YM-53403 Biological Activity

Description YM-53403 (YM53403) is a specific anti-respiratory syncytial virus (RSV) agent with EC50 of 0.2 uM in plaque reduction assays; displays 100-fold more potent than ribavirin, an attractive compound for the treatment of RSV infection.
References References 1. Sudo K, et al. Antiviral Res. 2005 Feb;65(2):125-31. 2. Tiong-Yip CL, et al. Antimicrob Agents Chemother. 2014 Jul;58(7):3867-73. View Related Products by Target RSV

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 787.9±60.0 °C at 760 mmHg
Molecular Formula C36H29N3O3S
Molecular Weight 583.699
Flash Point 430.3±32.9 °C
Exact Mass 583.192932
LogP 5.83
Vapour Pressure 0.0±2.7 mmHg at 25°C
Index of Refraction 1.734

 Synonyms

6-{4-[(2-Biphenylylcarbonyl)amino]benzoyl}-N-cyclopropyl-5,6-dihydro-4H-thieno[3,2-d][1]benzazepine-2-carboxamide
4H-Thieno[3,2-d][1]benzazepine-2-carboxamide, 6-[4-[([1,1'-biphenyl]-2-ylcarbonyl)amino]benzoyl]-N-cyclopropyl-5,6-dihydro-
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