Pyr-His-Pro-Gly-OH

Modify Date: 2024-01-12 21:17:05

Pyr-His-Pro-Gly-OH Structure
Pyr-His-Pro-Gly-OH structure
Common Name Pyr-His-Pro-Gly-OH
CAS Number 85344-77-0 Molecular Weight 420.42000
Density 1.461g/cm3 Boiling Point 1069.5ºC at 760 mmHg
Molecular Formula C18H24N6O6 Melting Point N/A
MSDS N/A Flash Point 600.6ºC

 Use of Pyr-His-Pro-Gly-OH


Trh-gly (TRH-glycine) is a precursor of thyrotropin (TSH)-releasing hormone (TRH) that can release thyrotropin and prolactin[1].

 Names

Name TRH-Gly
Synonym More Synonyms

 Pyr-His-Pro-Gly-OH Biological Activity

Description Trh-gly (TRH-glycine) is a precursor of thyrotropin (TSH)-releasing hormone (TRH) that can release thyrotropin and prolactin[1].
Related Catalog
In Vitro 在表达内源性 TRH-R 的 GH3 细胞中,Trh-gly 引起细胞内钙浓度的立即升高,表明 Trh-gly 直接反应而不从 Trh-gly 转化为 TRH[2]。
In Vivo 在聚氨酯麻醉的 2 个月大(250 克)雄性 Sprague-Dawley 大鼠中,Trh-gly(脑池内注射;1.0 mg)导致下丘脑、延髓和血液中的 TRH 水平显着增加[1]。
References

[1]. A E Pekary, et al. Release of thyrotropin and prolactin by a thyrotropin-releasing hormone (TRH) precursor, TRH-Gly: conversion to TRH is sufficient for in vivo effects. Neuroendocrinology. 1990 Dec;52(6):618-25.  

[2]. M Yamada, et al. Activation of the thyrotropin-releasing hormone (TRH) receptor by a direct precursor of TRH, TRH-Gly. Neurosci Lett. 1995 Aug 18;196(1-2):109-12.  

 Chemical & Physical Properties

Density 1.461g/cm3
Boiling Point 1069.5ºC at 760 mmHg
Molecular Formula C18H24N6O6
Molecular Weight 420.42000
Flash Point 600.6ºC
Exact Mass 420.17600
PSA 173.59000
Index of Refraction 1.611

 Synonyms

PE-H-P-G
PYR-HIS-PRO-GLY-OH
THYROTROPIN-RELEASING HORMONE-GLY
pglu-his-pro-gly
PYR-HIS-PRO-GLY
GLP-HIS-PRO-GLY
Top Suppliers:I want be here


Get all suppliers and price by the below link:

Pyr-His-Pro-Gly-OH suppliers

Pyr-His-Pro-Gly-OH price