CMA-008
Modify Date: 2022-11-21 19:09:38
CMA-008 structure
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Common Name | CMA-008 | ||
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| CAS Number | 854091-96-6 | Molecular Weight | 308.075 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C8H9IN2O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CMA-008CMA-008 is a cell-permeable, small molecule modulator of NAADP-mediated Ca2+ release, competes with NAADP binding, inhibit Ca2+ release via the NAADP receptor (IC50=15 uM-1 mM); selectively ablates NAADP-dependent Ca2+ oscillations induced by the external gastric peptide hormone agonist cholecystokinin (CCK) in murine pancreatic acinar cells. |
| Name | CMA-008 |
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| Description | CMA-008 is a cell-permeable, small molecule modulator of NAADP-mediated Ca2+ release, competes with NAADP binding, inhibit Ca2+ release via the NAADP receptor (IC50=15 uM-1 mM); selectively ablates NAADP-dependent Ca2+ oscillations induced by the external gastric peptide hormone agonist cholecystokinin (CCK) in murine pancreatic acinar cells. |
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| References | References 1. Dowden J, et al. Chem Biol. 2006 Jun;13(6):659-65. 2. Dammermann W, et al. Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10678-83. View Related Products by Target Other Targets |
| Molecular Formula | C8H9IN2O3 |
|---|---|
| Molecular Weight | 308.075 |