CW 008
Modify Date: 2024-02-03 18:39:59
CW 008 structure
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Common Name | CW 008 | ||
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| CAS Number | 1134613-19-6 | Molecular Weight | 420.372 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C21H14F2N6O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CW 008CW 008, a derivative of pyrazole-pyridine, is a CREB or PKA pathway agonist. CW 008 also is a stem cell differentiating agent. CW 008 stimulates osteoblast differentiation of human MSCs and increases bone formation in ovariectomized mice. CW008 promotes osteogenesis by activating cAMP/PKA/CREB signaling pathway and inhibiting leptin secretion[1][2][3]. |
| Name | 4-Fluoro-N-[5-fluoro-6-(5-methoxypyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl]benzamide |
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| Synonym | More Synonyms |
| Description | CW 008, a derivative of pyrazole-pyridine, is a CREB or PKA pathway agonist. CW 008 also is a stem cell differentiating agent. CW 008 stimulates osteoblast differentiation of human MSCs and increases bone formation in ovariectomized mice. CW008 promotes osteogenesis by activating cAMP/PKA/CREB signaling pathway and inhibiting leptin secretion[1][2][3]. |
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| Related Catalog | |
| Target |
PKA |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Molecular Formula | C21H14F2N6O2 |
| Molecular Weight | 420.372 |
| Exact Mass | 420.114624 |
| LogP | 3.46 |
| Index of Refraction | 1.726 |
| Benzamide, 4-fluoro-N-[5-fluoro-6-(5-methoxypyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl]- |
| 4-Fluoro-N-[5-fluoro-6-(5-methoxypyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl]benzamide |