Curculigoside
Modify Date: 2025-08-21 11:21:46
Curculigoside structure
|
Common Name | Curculigoside | ||
|---|---|---|---|---|
| CAS Number | 85643-19-2 | Molecular Weight | 466.435 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 734.9±60.0 °C at 760 mmHg | |
| Molecular Formula | C22H26O11 | Melting Point | 158-160ºC | |
| MSDS | N/A | Flash Point | 253.8±26.4 °C | |
Use of CurculigosideCurculigoside is the main saponin in C. orchioide, exerts significant antioxidant, anti-osteoporosis, antidepressant and neuroprotection effects. Curculigoside possesses significant anti-arthritic effects in vivo and in vitro via regulation of the JAK/STAT/NF-κB signaling pathway[1]. |
| Name | curculigoside |
|---|---|
| Synonym | More Synonyms |
| Description | Curculigoside is the main saponin in C. orchioide, exerts significant antioxidant, anti-osteoporosis, antidepressant and neuroprotection effects. Curculigoside possesses significant anti-arthritic effects in vivo and in vitro via regulation of the JAK/STAT/NF-κB signaling pathway[1]. |
|---|---|
| Related Catalog | |
| Target |
JAK; STAT; NF-κB[1] |
| In Vitro | Curculigoside (1-64 μg/ml; 72 hours) exerts significant inhibitory effects on MH7A cell viability between 1 and 64 µg/ml in MH7A cells[1]. Curculigoside (4-16 μg/ml; 24 hours) decreases the protein expression of JAK1, JAK3 and STAT3 compared to the TNF-α group[1]. Cell Viability Assay[1] Cell Line: MH7A cells Concentration: 1 μg/ml; 2 μg/ml; 4 μg/ml; 8 μg/ml; 16 μg/ml; 32 μg/ml; 64 μg/ml Incubation Time: 72 hours Result: Had inhibitory effect on MH7A cells. Western Blot Analysis[1] Cell Line: MH7A cells Concentration: 4 μg/ml; 64 μg/ml Incubation Time: 24 hours Result: Downregulated JAK1, JAK3 and STAT3 protein expression. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 734.9±60.0 °C at 760 mmHg |
| Melting Point | 158-160ºC |
| Molecular Formula | C22H26O11 |
| Molecular Weight | 466.435 |
| Flash Point | 253.8±26.4 °C |
| Exact Mass | 466.147522 |
| PSA | 164.37000 |
| LogP | -0.02 |
| Vapour Pressure | 0.0±2.5 mmHg at 25°C |
| Index of Refraction | 1.624 |
| InChIKey | SJJRKHVKAXVFJQ-QKYBYQKWSA-N |
| SMILES | COc1cccc(OC)c1C(=O)OCc1cc(O)ccc1OC1OC(CO)C(O)C(O)C1O |
| Safety Phrases | 24/25 |
|---|---|
| HS Code | 29389090 |
| β-D-Glucopyranoside, 2-(((2,6-dimethoxybenzoyl)oxy)methyl)-4-hydroxyphenyl |
| Curculigoside A |
| 2-(β-D-Glucopyranosyloxy)-5-hydroxybenzyl 2,6-dimethoxybenzoate |
| Benzoic acid, 2,6-dimethoxy-, [2-(β-D-glucopyranosyloxy)-5-hydroxyphenyl]methyl ester |
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- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Curculigoside
- Price: Check
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Curculigoside
- Price: ￥1178.0/20mg
- Purity: 98.0%
- Delivery: 1 Day
- Contact: Liu jia
- Email: 2130147988@qq.com
- DC Chemicals Limited
- China
- Product Name: Curculigoside
- Price: $280.0/20mg
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: CURCULIGOSIDE
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
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