DL-AP7

Modify Date: 2024-01-02 18:56:32

DL-AP7 structure	Common Name	DL-AP7
	CAS Number	85797-13-3	Molecular Weight	225.17900
	Density	1.39g/cm3	Boiling Point	480.1ºC at 760mmHg
	Molecular Formula	C₇H₁₆NO₅P	Melting Point	N/A
	MSDS	USA	Flash Point	244.2ºC

Use of DL-AP7

DL-AP7 is a competitive NMDA antagonist and an anticonvulsant. DL-AP7 blocks the NMDA-induced convulsions and impairs learning performance in a passive avoidance task in mice[1].

Name	2-Amino-7-phosphonoheptanoic acid
Synonym	More Synonyms

Description	DL-AP7 is a competitive NMDA antagonist and an anticonvulsant. DL-AP7 blocks the NMDA-induced convulsions and impairs learning performance in a passive avoidance task in mice[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
In Vivo	DL-AP7 (ICV) blocks the NMDA-induced convulsions (ED50=0.22 nmol/mouse) and impairs learning performance in a passive avoidance task in mice[1].
References	[1]. Chiamulera C, et al. Effect of NMDA- and strychnine-insensitive glycine site antagonists on NMDA-mediated convulsions and learning. Psychopharmacology (Berl). 1990;102(4):551-552.

Density	1.39g/cm3
Boiling Point	480.1ºC at 760mmHg
Molecular Formula	C₇H₁₆NO₅P
Molecular Weight	225.17900
Flash Point	244.2ºC
Exact Mass	225.07700
PSA	130.66000
LogP	0.83670

DL-AP7 MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MJ1927500

CHEMICAL NAME :: Heptanoic acid, 2-amino-7-phosphono-

CAS REGISTRY NUMBER :: 85797-13-3

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C7-H16-N-O5-P

MOLECULAR WEIGHT :: 225.21

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001, 00-068 Warsaw 1, Poland) V.25- 1973- Volume(issue)/page/year: 37,575,1985

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	22-24/25
RIDADR	NONH for all modes of transport
RTECS	MJ1927500
HS Code	2931900090

(N-acetylamino-...

CAS#:85685-91-2

~75%

DL-AP7

CAS#:85797-13-3

Literature: Aboujaoude, E. Elia; Collignon, N.; Savignac, P.; Bensoam, J. Phosphorus and Sulfur and the Related Elements, 1987 , vol. 34, p. 93 - 104

diethyl 2-aceta...

CAS#:5183-26-6

DL-AP7

CAS#:85797-13-3

Literature: Aboujaoude, E. Elia; Collignon, N.; Savignac, P.; Bensoam, J. Phosphorus and Sulfur and the Related Elements, 1987 , vol. 34, p. 93 - 104

N/A

CAS#:137622-48-1

DL-AP7

CAS#:85797-13-3

Literature: Ragulin, V. V.; Bofanova, M. E.; Tsvetkov, Eugene N. Phosphorus, Sulfur and Silicon and the Related Elements, 1991 , vol. 62, # 14 p. 237 - 242

1,5-Dibromopentane

CAS#:111-24-0

DL-AP7

CAS#:85797-13-3

Literature: Aboujaoude, E. Elia; Collignon, N.; Savignac, P.; Bensoam, J. Phosphorus and Sulfur and the Related Elements, 1987 , vol. 34, p. 93 - 104

diethyl 2-aceta...

CAS#:137622-51-6

DL-AP7

CAS#:85797-13-3

Literature: Ragulin, V. V.; Bofanova, M. E.; Tsvetkov, Eugene N. Phosphorus, Sulfur and Silicon and the Related Elements, 1991 , vol. 62, # 14 p. 237 - 242

Precursor 3
CAS#:85685-91-2 (N-acetylamino-... CAS#:5183-26-6 diethyl 2-aceta... CAS#:111-24-0 1,5-Dibromopentane
DownStream 0

HS Code	2931900090
Summary	2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

Differentiation of neurons restricts Arbovirus replication and increases expression of the alpha isoform of IRF-7.

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Susceptibility to alphavirus infection is age dependent, and host maturation is associated with decreased virus replication and less severe encephalitis. To identify factors associated with maturation...

Effect of barodenervation on cardiovascular responses elicited from the hypothalamic arcuate nucleus of the rat.

PLoS ONE 7(12) , e53111, (2012)

We have previously reported that chemical stimulation of the hypothalamic arcuate nucleus (ARCN) in the rat elicited increases as well as decreases in blood pressure (BP) and sympathetic nerve activit...

L-NOARG-induced catalepsy can be influenced by glutamatergic neurotransmission mediated by NMDA receptors in the inferior colliculus.

Behav. Brain Res. 234(2) , 149-54, (2012)

The inferior colliculus (IC), a midbrain structure that processes acoustic information of aversive nature, is distinguished from other auditory nuclei in the brainstem by its connections with structur...

2-amino-5-phosphonovaleric acid

acide amino-6 carboxy-6 hexylphosphonique

2-amino-5-phosphopentanoicacid

DL-APV

[3H]-DL-AP7

D-2-amino-5-phosphonovaleric acid

[3H]-DL-AP 5

DL-2-amino-5-phosphonovaleric acid

d-(+/-)-2-amino-5-phosphonopentanoic acid

5-PHOSPHONO-DL-NORVALINE

(-)2-amino-7-phosphonoheptanoic acid

AP-5

APV

2-amino-5-phosphovaleric acid

DC Chemicals Limited
China
Product Name: DL-AP7
Price: $300.0/100mg $500.0/250mg $1000.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: (+/-)-2-AMINO-7-PHOSPHONOHEPTANOIC
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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