DL-AP7
DL-AP7 structure
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Common Name | DL-AP7 | ||
|---|---|---|---|---|
| CAS Number | 85797-13-3 | Molecular Weight | 225.17900 | |
| Density | 1.39g/cm3 | Boiling Point | 480.1ºC at 760mmHg | |
| Molecular Formula | C7H16NO5P | Melting Point | N/A | |
| MSDS | USA | Flash Point | 244.2ºC | |
Use of DL-AP7DL-AP7 is a competitive NMDA antagonist and an anticonvulsant. DL-AP7 blocks the NMDA-induced convulsions and impairs learning performance in a passive avoidance task in mice[1]. |
| Name | 2-Amino-7-phosphonoheptanoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | DL-AP7 is a competitive NMDA antagonist and an anticonvulsant. DL-AP7 blocks the NMDA-induced convulsions and impairs learning performance in a passive avoidance task in mice[1]. |
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| Related Catalog | |
| In Vivo | DL-AP7 (ICV) blocks the NMDA-induced convulsions (ED50=0.22 nmol/mouse) and impairs learning performance in a passive avoidance task in mice[1]. |
| References |
| Density | 1.39g/cm3 |
|---|---|
| Boiling Point | 480.1ºC at 760mmHg |
| Molecular Formula | C7H16NO5P |
| Molecular Weight | 225.17900 |
| Flash Point | 244.2ºC |
| Exact Mass | 225.07700 |
| PSA | 130.66000 |
| LogP | 0.83670 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | 22-24/25 |
| RIDADR | NONH for all modes of transport |
| RTECS | MJ1927500 |
| HS Code | 2931900090 |
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~75%
DL-AP7 CAS#:85797-13-3 |
| Literature: Aboujaoude, E. Elia; Collignon, N.; Savignac, P.; Bensoam, J. Phosphorus and Sulfur and the Related Elements, 1987 , vol. 34, p. 93 - 104 |
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DL-AP7 CAS#:85797-13-3 |
| Literature: Aboujaoude, E. Elia; Collignon, N.; Savignac, P.; Bensoam, J. Phosphorus and Sulfur and the Related Elements, 1987 , vol. 34, p. 93 - 104 |
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~%
DL-AP7 CAS#:85797-13-3 |
| Literature: Ragulin, V. V.; Bofanova, M. E.; Tsvetkov, Eugene N. Phosphorus, Sulfur and Silicon and the Related Elements, 1991 , vol. 62, # 14 p. 237 - 242 |
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~%
DL-AP7 CAS#:85797-13-3 |
| Literature: Aboujaoude, E. Elia; Collignon, N.; Savignac, P.; Bensoam, J. Phosphorus and Sulfur and the Related Elements, 1987 , vol. 34, p. 93 - 104 |
|
~%
DL-AP7 CAS#:85797-13-3 |
| Literature: Ragulin, V. V.; Bofanova, M. E.; Tsvetkov, Eugene N. Phosphorus, Sulfur and Silicon and the Related Elements, 1991 , vol. 62, # 14 p. 237 - 242 |
| Precursor 3 | |
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| DownStream 0 | |
| HS Code | 2931900090 |
|---|---|
| Summary | 2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0% |
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Differentiation of neurons restricts Arbovirus replication and increases expression of the alpha isoform of IRF-7.
J. Virol. 89(1) , 48-60, (2014) Susceptibility to alphavirus infection is age dependent, and host maturation is associated with decreased virus replication and less severe encephalitis. To identify factors associated with maturation... |
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Effect of barodenervation on cardiovascular responses elicited from the hypothalamic arcuate nucleus of the rat.
PLoS ONE 7(12) , e53111, (2012) We have previously reported that chemical stimulation of the hypothalamic arcuate nucleus (ARCN) in the rat elicited increases as well as decreases in blood pressure (BP) and sympathetic nerve activit... |
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L-NOARG-induced catalepsy can be influenced by glutamatergic neurotransmission mediated by NMDA receptors in the inferior colliculus.
Behav. Brain Res. 234(2) , 149-54, (2012) The inferior colliculus (IC), a midbrain structure that processes acoustic information of aversive nature, is distinguished from other auditory nuclei in the brainstem by its connections with structur... |
| 2-amino-5-phosphonovaleric acid |
| acide amino-6 carboxy-6 hexylphosphonique |
| 2-amino-5-phosphopentanoicacid |
| DL-APV |
| [3H]-DL-AP7 |
| D-2-amino-5-phosphonovaleric acid |
| [3H]-DL-AP 5 |
| DL-2-amino-5-phosphonovaleric acid |
| d-(+/-)-2-amino-5-phosphonopentanoic acid |
| 5-PHOSPHONO-DL-NORVALINE |
| (-)2-amino-7-phosphonoheptanoic acid |
| AP-5 |
| APV |
| 2-amino-5-phosphovaleric acid |