Glyco-Obeticholic acid
Modify Date: 2024-01-16 20:22:31
Glyco-Obeticholic acid structure
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Common Name | Glyco-Obeticholic acid | ||
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| CAS Number | 863239-60-5 | Molecular Weight | 477.68 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H47NO5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Glyco-Obeticholic acidGlyco-obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is a farnesoid X receptor (FXR) agonist[1]. |
| Name | Glyco-Obeticholic acid |
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| Description | Glyco-obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is a farnesoid X receptor (FXR) agonist[1]. |
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| Related Catalog | |
| In Vitro | Obeticholic acid is conjugated with glycine in the liver to form glycol-obeticholic acid, which is secreted into bile. Microorganisms in the ileum and colon can deconjugate glyco-obeticholic acid, converting it into the parent drug, which may then be reabsorbed or excreted in faeces[1]. |
| References |
[1]. Markham A, et al. Obeticholic Acid: First Global Approval. Drugs. 2016 Aug;76(12):1221-6. |
| Molecular Formula | C28H47NO5 |
|---|---|
| Molecular Weight | 477.68 |