N-Methylcalycinine

Modify Date: 2025-08-25 18:39:33

N-Methylcalycinine Structure
N-Methylcalycinine structure
Common Name N-Methylcalycinine
CAS Number 86537-66-8 Molecular Weight 325.36
Density 1.3±0.1 g/cm3 Boiling Point 531.9±50.0 °C at 760 mmHg
Molecular Formula C19H19NO4 Melting Point N/A
MSDS N/A Flash Point 275.5±30.1 °C

 Use of N-Methylcalycinine


N-Methylcalycinine is a nature product with AChE inhibitory activity. N-Methylcalycinine can be isolated from the roots of Stephania epigaea. N-Methylcalycinine can be used for the research of asthma, cancer, dysentery, fever, hyperglycemia, intestinal complaints, inflammation, sleep disturbances, tuberculosis and so on[1].

 Names

Name (7aR)-10-Methoxy-7-methyl-6,7,7a,8-tetrahydro-5H-[1,3]benzodioxol o[6,5,4-de]benzo[g]quinolin-12-ol
Synonym More Synonyms

 N-Methylcalycinine Biological Activity

Description N-Methylcalycinine is a nature product with AChE inhibitory activity. N-Methylcalycinine can be isolated from the roots of Stephania epigaea. N-Methylcalycinine can be used for the research of asthma, cancer, dysentery, fever, hyperglycemia, intestinal complaints, inflammation, sleep disturbances, tuberculosis and so on[1].
Related Catalog
References

[1]. Dong JW, et al. Proaporphine and aporphine alkaloids with acetylcholinesterase inhibitory activity from Stephania epigaea. Fitoterapia. 2015 Jul;104:102-7.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 531.9±50.0 °C at 760 mmHg
Molecular Formula C19H19NO4
Molecular Weight 325.36
Flash Point 275.5±30.1 °C
Exact Mass 325.131409
PSA 51.16000
LogP 3.55
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.654
InChIKey SFOMHAXOBRLRFH-CYBMUJFWSA-N
SMILES COc1cc(O)c2c(c1)CC1c3c(cc4c(c3-2)OCO4)CCN1C

 Safety Information

Hazard Codes Xi

 Synthetic Route

~61%

N-Methylcalycinine Structure

N-Methylcalycinine

CAS#:86537-66-8

Literature: Roblot, F.; Hocquemiller, R.; Cave, A. Bulletin de la Societe Chimique de France, 1990 , # 2 p. 258 - 267

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N-Methylcalycinine Structure

N-Methylcalycinine

CAS#:86537-66-8

Literature: Roblot, F.; Hocquemiller, R.; Cave, A. Bulletin de la Societe Chimique de France, 1990 , # 2 p. 258 - 267

~%

N-Methylcalycinine Structure

N-Methylcalycinine

CAS#:86537-66-8

Literature: Roblot, F.; Hocquemiller, R.; Cave, A. Bulletin de la Societe Chimique de France, 1990 , # 2 p. 258 - 267

 Synonyms

N-methylfissoldine
(7aR)-10-Methoxy-7-methyl-6,7,7a,8-tetrahydro-5H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinolin-12-ol
N-methylcalycinine
4-Dimethylamino-benzaldoxim-N-methylaether
<4-Dimethylamino-benzyliden>-methylamin-N-oxyd
5H-1,3-Benzodioxolo[6,5,4-de]benzo[g]quinolin-12-ol, 6,7,7a,8-tetrahydro-10-methoxy-7-methyl-, (7aR)-
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