Gastrofensin AN 5 free base

Modify Date: 2024-02-05 06:38:48

Gastrofensin AN 5 free base Structure
Gastrofensin AN 5 free base structure
Common Name Gastrofensin AN 5 free base
CAS Number 89845-16-9 Molecular Weight 344.84
Density N/A Boiling Point N/A
Molecular Formula C19H21ClN2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Gastrofensin AN 5 free base


Gastrofensin AN 5 free base, a 4-phenyl-tetrahydroisoquinoline derivative, is an antiulcer agent.

 Names

Name Gastrofensin AN 5 free base

 Gastrofensin AN 5 free base Biological Activity

Description Gastrofensin AN 5 free base, a 4-phenyl-tetrahydroisoquinoline derivative, is an antiulcer agent.
Related Catalog
In Vivo Gastrofensin AN 5 supresses the formation of ulcers in all experimental models. From the broad pharmacological studies of Gastrofensin AN 5 on this model it can be seen that even a dose of 0.100 mg/kg has a high antiulcer activity. The increase of the dose leads to a regular increase of the antiulcer activity, the highest suppression of the ulcer index being reaches at a dose of 1 mg/kg (86.15%). The comparative studies with Ranitidine and Cimetidine on the same experimental models of gastric ulcers show that Gastrofensin AN 5 possesses an antiulcer activity many times higher than that of the above-mentioned drugs[1].
References

[1]. Ivanova N, et al. A new class of antiulcer drugs. I. Antiulcer effect of AN5, a 4-phenyl-tetrahydroisoquinoline derivative, on different experimental models of ulcer in rats. Methods Find Exp Clin Pharmacol. 1990 Jul-Aug;12(6):401-10.

 Chemical & Physical Properties

Molecular Formula C19H21ClN2O2
Molecular Weight 344.84
Storage condition 2-8℃
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