PQ 69

Modify Date: 2024-01-29 10:03:53

PQ 69 structure	Common Name	PQ 69
	CAS Number	910045-32-8	Molecular Weight	350.39
	Density	1.3±0.1 g/cm3	Boiling Point	553.1±60.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₁₉FN₄O	Melting Point	N/A
	MSDS	N/A	Flash Point	288.3±32.9 °C

Use of PQ 69

PQ-69 is a potent and selective adenosine A1 receptor antagonist with inverse agonist activity. PQ-69 binds to hA1 receptor with a Ki value of 0.96 nM, is 217-fold more selective compared with hA2A receptors (Ki=208 nM) and >1,000-fold selectivity over hA3 receptor (Ki >100 μM). PQ-69 can be used for the research of renal dysfunction[1].

Name	PQ 69
Synonym	More Synonyms

Description	PQ-69 is a potent and selective adenosine A1 receptor antagonist with inverse agonist activity. PQ-69 binds to hA1 receptor with a Ki value of 0.96 nM, is 217-fold more selective compared with hA2A receptors (Ki=208 nM) and >1,000-fold selectivity over hA3 receptor (Ki >100 μM). PQ-69 can be used for the research of renal dysfunction[1].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor
References	[1]. Min Lu, et al. PQ-69, a novel and selective adenosine A1 receptor antagonist with inverse agonist activity. Purinergic Signal. 2014 Dec;10(4):619-29.

Density	1.3±0.1 g/cm3
Boiling Point	553.1±60.0 °C at 760 mmHg
Molecular Formula	C₂₀H₁₉FN₄O
Molecular Weight	350.39
Flash Point	288.3±32.9 °C
Exact Mass	350.154297
LogP	3.64
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.674

3H-Pyrazolo[4,3-c]quinolin-3-one, 4-(butylamino)-2-(3-fluorophenyl)-1,2-dihydro-

MFCD30182281

4-(Butylamino)-2-(3-fluorophenyl)-1,2-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: PQ 69
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Purity: 98.0%
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