2-Ethacrolein

Modify Date: 2024-01-02 18:46:49

2-Ethacrolein Structure
2-Ethacrolein structure
Common Name 2-Ethacrolein
CAS Number 922-63-4 Molecular Weight 84.116
Density 0.8±0.1 g/cm3 Boiling Point 92.5±0.0 °C at 760 mmHg
Molecular Formula C5H8O Melting Point -101.15°C (estimate)
MSDS Chinese USA Flash Point 1.1±0.0 °C
Symbol GHS02 GHS06
GHS02, GHS06
Signal Word Danger

 Names

Name 2-Ethylacrolein
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.8±0.1 g/cm3
Boiling Point 92.5±0.0 °C at 760 mmHg
Melting Point -101.15°C (estimate)
Molecular Formula C5H8O
Molecular Weight 84.116
Flash Point 1.1±0.0 °C
Exact Mass 84.057518
PSA 17.07000
LogP 1.07
Vapour Pressure 51.5±0.1 mmHg at 25°C
Index of Refraction 1.399
Storage condition 2-8°C
Water Solubility Soluble in alcohol. Insoluble in water.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ES3480000
CHEMICAL NAME :
Butyraldehyde, 2-methylene-
CAS REGISTRY NUMBER :
922-63-4
BEILSTEIN REFERENCE NO. :
1098378
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C5-H8-O
MOLECULAR WEIGHT :
84.13

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
289 ppm/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
48400 ppb/6H/13W-I
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - changes in lung weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Related to Chronic Data - changes in ovarian weight

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
1 umol/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 264,193,1991

 Safety Information

Symbol GHS02 GHS06
GHS02, GHS06
Signal Word Danger
Hazard Statements H225-H302 + H312-H330
Precautionary Statements P210-P260-P280-P284-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes F:Flammable;Xn:Harmful;
Risk Phrases R11;R20/21/22
Safety Phrases S16-S26-S28-S36/37/39
RIDADR UN 3384
RTECS ES3480000
Packaging Group II
HS Code 2912190090

 Synthetic Route

 Customs

HS Code 2912190090
Summary 2912190090 acyclic aldehydes without other oxygen function。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

 Articles5

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An efficient approach to Aspidosperma alkaloids via [4 + 2] cycloadditions of aminosiloxydienes: stereocontrolled total synthesis of (+/-)-tabersonine. Gram-scale catalytic asymmetric syntheses of (+)-tabersonine and (+)-16-methoxytabersonine. Asymmetric syntheses of (+)-aspidospermidine and (-)-quebrachamine.

J. Am. Chem. Soc. 124(17) , 4628-41, (2002)

Described is a concise, highly stereocontrolled strategy to the Aspidosperma family of indole alkaloids, one that is readily adapted to the asymmetric synthesis of these compounds. The strategy is dem...

Immunological response from an entirely carbohydrate antigen: design of synthetic vaccines based on Tn-PS A1 conjugates.

J. Am. Chem. Soc. 131(28) , 9622-3, (2009)

An entirely carbohydrate-based immunogen consisting of a zwitterionic polysaccharide (ZPS) PS A1 and the well-known tumor antigen Tn has been designed, synthesized, and studied for immunological effec...

Mutagenicity of 2-methylacrolein, 2-ethylacrolein and 2-propylacrolein in Salmonella typhimurium TA100. A comparative study.

Mutat. Res. 264(4) , 193-6, (1991)

The C2-alkylated acrolein derivatives 2-methylacrolein, 2-ethylacrolein and 2-propylacrolein are mutagenic in Salmonella typhimurium TA100. They are direct mutagens, their mutagenic potency being inve...

 Synonyms

MFCD00010129
Butanal, 2-methylene-
2-Ethacrolein
2-Ethylacrolein
EINECS 213-079-3
α-ethylacrolein
2-Methylenebutanal
2-methylidenebutanal
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