Iodoacetyl-LC-biotin

Modify Date: 2025-08-25 16:28:43

Iodoacetyl-LC-biotin Structure
Iodoacetyl-LC-biotin structure
Common Name Iodoacetyl-LC-biotin
CAS Number 93285-75-7 Molecular Weight 510.43300
Density 1.414g/cm3 Boiling Point 793.7ºC at 760 mmHg
Molecular Formula C18H31IN4O3S Melting Point N/A
MSDS N/A Flash Point 433.8ºC

 Use of Iodoacetyl-LC-biotin


Iodoacetyl-LC-biotin is a biotinylated electrophile probe that can be used to investigate the scope and characteristics of protein covalent binding to subcellular proteomes[1][2].

 Names

Name n-iodoacetyl-n-biotinylhexylenediamine
Synonym More Synonyms

 Iodoacetyl-LC-biotin Biological Activity

Description Iodoacetyl-LC-biotin is a biotinylated electrophile probe that can be used to investigate the scope and characteristics of protein covalent binding to subcellular proteomes[1][2].
Related Catalog
In Vitro Iodoacetyl-LC-biotin (IAB) (50-200 μM; 6-24 h) increases LDH leakage in HEK293 cells in a time- and dose-dependant manner[1]. IAB (50-200 µM; 24 h) causes the release of cytochrome c from the mitochondria to the cytosol in HEK293 cells[1].
References

[1]. Wong HL, et, al. Mitochondrial protein targets of thiol-reactive electrophiles. Chem Res Toxicol. 2008 Apr;21(4):796-804.

[2]. Davis KA, et, al. Staining of cell surface human CD4 with 2'-F-pyrimidine-containing RNA aptamers for flow cytometry. Nucleic Acids Res. 1998 Sep 1;26(17):3915-24.

 Chemical & Physical Properties

Density 1.414g/cm3
Boiling Point 793.7ºC at 760 mmHg
Molecular Formula C18H31IN4O3S
Molecular Weight 510.43300
Flash Point 433.8ºC
Exact Mass 510.11600
PSA 124.63000
LogP 3.37940
Index of Refraction 1.559
InChIKey DNXDWMHPTVQBIP-ZQIUZPCESA-N
SMILES O=C(CI)NCCCCCCNC(=O)CCCCC1SCC2NC(=O)NC21

 Safety Information

Hazard Codes Xi

 Synonyms

N-Iodoacetyl-N'-biotinyl-1,6-hexanediamine
N-IODOACETYL-N'-BIOTINYLHEXYLENEDIAMINE
iodoacetyl-LC-biotin
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