PKN1/2-IN-1

Modify Date: 2024-04-05 15:35:25

PKN1/2-IN-1 Structure
PKN1/2-IN-1 structure
 Common Name PKN1/2-IN-1
CAS Number 942425-34-5 Molecular Weight 241.29
Density N/A Boiling Point N/A
Molecular Formula C14H15N3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PKN1/2-IN-1


PKN1/2-IN-1 is a potent, cell penetrant and selective PKN2 (PRK2) inhibitor (IC50=16 nM; Ki=8 nM)[1].

 Names

Name PKN1/2-IN-1

 PKN1/2-IN-1 Biological Activity

Description PKN1/2-IN-1 is a potent, cell penetrant and selective PKN2 (PRK2) inhibitor (IC50=16 nM; Ki=8 nM)[1].
Related Catalog
Target

IC50: 16 nM, Ki: 8 nM (PKN2)[1] IC50: 108 nM, Ki: 210 nM (PKN1)[1].

References

[1]. Scott F, et al. Development of dihydropyrrolopyridinone-based PKN2/PRK2 chemical tools to enable drug discovery. Bioorg Med Chem Lett. 2022;60:128588.

 Chemical & Physical Properties

Molecular Formula C14H15N3O
Molecular Weight 241.29
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Chemsrc provides PKN1/2-IN-1(CAS#:942425-34-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of PKN1/2-IN-1 are included as well.>> amp version: PKN1/2-IN-1

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