IDO1/2-IN-1 hydrochloride

Modify Date: 2025-08-27 15:48:54

IDO1/2-IN-1 hydrochloride Structure
IDO1/2-IN-1 hydrochloride structure
Common Name IDO1/2-IN-1 hydrochloride
CAS Number 2310286-60-1 Molecular Weight 521.73
Density N/A Boiling Point N/A
Molecular Formula C16H19BrClFN8O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IDO1/2-IN-1 hydrochloride


IDO1/2-IN-1 hydrochloride (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively. IDO1/2-IN-1 hydrochloride exhibits antitumor activies. Orally active[1].

 Names

Name IDO1/2-IN-1 hydrochloride

 IDO1/2-IN-1 hydrochloride Biological Activity

Description IDO1/2-IN-1 hydrochloride (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively. IDO1/2-IN-1 hydrochloride exhibits antitumor activies. Orally active[1].
Related Catalog
References

[1]. He X, et al. Discovery of the First Potent IDO1/IDO2 Dual Inhibitors: A Promising Strategy for Cancer Immunotherapy. J Med Chem. 2021;64(24):17950-17968.

 Chemical & Physical Properties

Molecular Formula C16H19BrClFN8O4
Molecular Weight 521.73
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