IDO1/2-IN-1 hydrochloride

Modify Date: 2024-01-09 17:51:09

IDO1/2-IN-1 hydrochloride structure	Common Name	IDO1/2-IN-1 hydrochloride
	CAS Number	2310286-60-1	Molecular Weight	521.73
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₁₉BrClFN₈O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of IDO1/2-IN-1 hydrochloride

IDO1/2-IN-1 hydrochloride (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively. IDO1/2-IN-1 hydrochloride exhibits antitumor activies. Orally active[1].

Name	IDO1/2-IN-1 hydrochloride

Description	IDO1/2-IN-1 hydrochloride (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively. IDO1/2-IN-1 hydrochloride exhibits antitumor activies. Orally active[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Indoleamine 2,3-Dioxygenase (IDO)
References	[1]. He X, et al. Discovery of the First Potent IDO1/IDO2 Dual Inhibitors: A Promising Strategy for Cancer Immunotherapy. J Med Chem. 2021;64(24):17950-17968.

Molecular Formula	C₁₆H₁₉BrClFN₈O₄
Molecular Weight	521.73

IDO1/2-IN-1 hydrochloride

Use of IDO1/2-IN-1 hydrochloride

Names

IDO1/2-IN-1 hydrochloride Biological Activity

Chemical & Physical Properties