Biotin-PEG11-Mal

Modify Date: 2024-01-09 01:43:15

Biotin-PEG11-Mal Structure
Biotin-PEG11-Mal structure
Common Name Biotin-PEG11-Mal
CAS Number 1646619-56-8 Molecular Weight 922.09
Density N/A Boiling Point N/A
Molecular Formula C41H71N5O16S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Biotin-PEG11-Mal


Biotin-PEG11-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Biotin-PEG11-Mal

 Biotin-PEG11-Mal Biological Activity

Description Biotin-PEG11-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C41H71N5O16S
Molecular Weight 922.09