Azido-PEG11-azide

Modify Date: 2024-01-09 21:11:34

Azido-PEG11-azide Structure
Azido-PEG11-azide structure
Common Name Azido-PEG11-azide
CAS Number 1392284-57-9 Molecular Weight 596.672
Density N/A Boiling Point N/A
Molecular Formula C24H48N6O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG11-azide


Azido-PEG11-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 1,35-Diazido-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontane
Synonym More Synonyms

 Azido-PEG11-azide Biological Activity

Description Azido-PEG11-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C24H48N6O11
Molecular Weight 596.672
Exact Mass 596.338135
LogP -3.09

 Synonyms

3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontane, 1,35-diazido-
1,35-Diazido-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontane