deoxynyboquinone
Modify Date: 2024-01-12 09:03:21
deoxynyboquinone structure
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Common Name | deoxynyboquinone | ||
|---|---|---|---|---|
| CAS Number | 96748-86-6 | Molecular Weight | 284.267 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 591.2±50.0 °C at 760 mmHg | |
| Molecular Formula | C15H12N2O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 311.4±30.1 °C | |
Use of deoxynyboquinoneDeoxynyboquinone (NSC 165572;DNQ) is a potent inducer of cancer cell death that induces death of cancer cells in culture with IC50 of 16-210 nM, a substrate for NAD(P)H:quinone oxidoreductase (NQO1); it's lethality relies on NQO1-dependent futile redox cycling that consumes oxygen and generates extensive reactive oxygen species (ROS). |
| Name | deoxynyboquinone |
|---|---|
| Synonym | More Synonyms |
| Description | Deoxynyboquinone (NSC 165572;DNQ) is a potent inducer of cancer cell death that induces death of cancer cells in culture with IC50 of 16-210 nM, a substrate for NAD(P)H:quinone oxidoreductase (NQO1); it's lethality relies on NQO1-dependent futile redox cycling that consumes oxygen and generates extensive reactive oxygen species (ROS). |
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| References | References 1. Bair JS, et al. J Am Chem Soc. 2010 Apr 21;132(15):5469-78. 2. Huang X, et al. Cancer Res. 2012 Jun 15;72(12):3038-47. 3. Lee HY, et al. ACS Chem Biol. 2017 May 19;12(5):1416-1424. View Related Products by Target Other Targets |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 591.2±50.0 °C at 760 mmHg |
| Molecular Formula | C15H12N2O4 |
| Molecular Weight | 284.267 |
| Flash Point | 311.4±30.1 °C |
| Exact Mass | 284.079712 |
| LogP | -0.41 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.659 |
| 1,4,6-Trimethylpyrido[3,2-g]quinoline-2,5,8,10(1H,9H)-tetrone |
| Pyrido[3,2-g]quinoline-2,5,8,10(1H,9H)-tetrone, 1,4,6-trimethyl- |
| deoxynyboquinone |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: [Perfemiker]Deoxynyboquinone,98%
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: Deoxynyboquinone
- Price: $1000.0/25mg $700.0/10mg $500.0/5mg
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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