BIRT 377
Modify Date: 2024-01-11 16:32:04
BIRT 377 structure
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Common Name | BIRT 377 | ||
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| CAS Number | 213211-10-0 | Molecular Weight | 442.13 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 518.8±60.0 °C at 760 mmHg | |
| Molecular Formula | C18H15BrCl2N2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 267.6±32.9 °C | |
Use of BIRT 377BIRT 377 is a potent amd orally bioavailable inhibitor of the interaction between intercellular adhesion molecule-1 (ICAM-1) and lymphocyte function-associated antigen-1 (LFA-1), with a Ki of 25.8 nM. BIRT 377 also inhibits the production of IL-2 in vivo. BIRT 377 can be used for researching inflammatory and immune disorders[1]. |
| Name | BIRT 377 |
|---|---|
| Synonym | More Synonyms |
| Description | BIRT 377 is a potent amd orally bioavailable inhibitor of the interaction between intercellular adhesion molecule-1 (ICAM-1) and lymphocyte function-associated antigen-1 (LFA-1), with a Ki of 25.8 nM. BIRT 377 also inhibits the production of IL-2 in vivo. BIRT 377 can be used for researching inflammatory and immune disorders[1]. |
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| Related Catalog | |
| Target |
Ki: 25.8 nM (LFA-1)[1] |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 518.8±60.0 °C at 760 mmHg |
| Molecular Formula | C18H15BrCl2N2O2 |
| Molecular Weight | 442.13 |
| Flash Point | 267.6±32.9 °C |
| Exact Mass | 439.969391 |
| LogP | 4.76 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.632 |
| (5R)-5-[(4-Bromophenyl)methyl]-3-(3,5-dichlorophenyl)-1,5-dimethyl-2,4-imidazolidinedione |
| 2,4-Imidazolidinedione, 5-[(4-bromophenyl)methyl]-3-(3,5-dichlorophenyl)-1,5-dimethyl-, (5R)- |
| (5R)-5-(4-Bromobenzyl)-3-(3,5-dichlorophenyl)-1,5-dimethyl-2,4-imidazolidinedione |
| (5R)-5-(4-bromobenzyl)-3-(3,5-dichlorophenyl)-1,5-dimethylimidazolidine-2,4-dione |