Giripladib

Modify Date: 2024-01-09 13:50:25

Giripladib structure	Common Name	Giripladib
	CAS Number	865200-20-0	Molecular Weight	745.25
	Density	1.29g/cm3	Boiling Point	N/A
	Molecular Formula	C₄₁H₃₆ClF₃N₂O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Giripladib

Giripladib (PLA-695) is a indole-based inhibitor of cytosolic phospholipase A2 (cPLA2). Giripladib can be used for osteoarthritis and breast cancer research[1][2].

Name	Giripladib
Synonym	More Synonyms

Description	Giripladib (PLA-695) is a indole-based inhibitor of cytosolic phospholipase A2 (cPLA2). Giripladib can be used for osteoarthritis and breast cancer research[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Phospholipase Research Areas >> Inflammation/Immunology
Target	cPLA2α
References	[1]. Kokotos G, et al. Inhibition of group IVA cytosolic phospholipase A2 by thiazolyl ketones in vitro, ex vivo, and in vivo. J Med Chem. 2014 Sep 25;57(18):7523-35. [2]. Liu S, et al. A novel lncRNA ROPM-mediated lipid metabolism governs breast cancer stem cell properties. J Hematol Oncol. 2021 Oct 29;14(1):178.

Density	1.29g/cm3
Molecular Formula	C₄₁H₃₆ClF₃N₂O₄S
Molecular Weight	745.25
Exact Mass	744.20400
PSA	96.78000
LogP	10.95850
Storage condition	-20°C

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Giripladib

Use of Giripladib

Names

Giripladib Biological Activity

Chemical & Physical Properties

Synonyms