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抑胃肽

抑胃肽用途

Gastric Inhibitory Peptide (GIP), human 是一种是胃功能抑制剂。

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抑胃肽名称

[ CAS 号 ]:
100040-31-1

[ 中文名 ]:
人胃抑素

[ 英文名 ]:
Gastric Inhibitory Polypeptide (human)

[英文别名 ]:

MFCD00081634
GIP, human
YAEGTFISDYSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQ
Gastric Inhibitory Peptide (GIP), human

抑胃肽生物活性

[ 描述 ]:

Gastric Inhibitory Peptide (GIP), human 是一种是胃功能抑制剂。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 代谢疾病

天然产物 >> 其他

多肽产品

[体外研究]

胃抑制多肽(GIP)对脂肪组织和脂质代谢发挥各种外周作用,从而导致餐后状态的脂质沉积增加,sup> [1]。

[参考文献]

[1]. Meier JJ, et al. Gastric inhibitory polypeptide: the neglected incretin revisited. Regul Pept. 2002 Jul 15;107(1-3):1-13.

[相关活性小分子]

抑胃肽物理化学性质

[ 分子式 ]:
C₂₂₆H₃₃₈N₆₀O₆₆S

[ 分子量 ]:
4983.53

[ 储存条件 ]:
-20°C

抑胃肽安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xn

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3.0

抑胃肽文献

Long-term persistence of hormonal adaptations to weight loss.

N. Engl. J. Med. 365 , 1597-1604, (2011)

After weight loss, changes in the circulating levels of several peripheral hormones involved in the homeostatic regulation of body weight occur. Whether these changes are transient or persist over tim...

Pleiotropic effects of GIP on islet function involve osteopontin.

Diabetes 60 , 2424-2433, (2011)

The incretin hormone GIP (glucose-dependent insulinotropic polypeptide) promotes pancreatic β-cell function by potentiating insulin secretion and β-cell proliferation. Recently, a combined analysis of...

Gastric inhibitory polypeptide and its receptor are expressed in the central nervous system and support neuronal survival.

Cent. Nerv. Syst. Agents Med. Chem. 11 , 210-222, (2011)

The development of neuronal apoptosis depends on an intrinsic transcriptional program. By DNA microarray technology, we have previously implicated a number of genes in different paradigms of neuronal ...

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抑胃肽