丁二腈
丁二腈用途
用作从石油馏分中萃取芳香烃的溶剂和镀镍的上光剂，也用于有机合成
【用途二】
主要用作喹吖酮类颜料的原料。此种颜料广泛应用于汽车和镀锌铁皮涂料、彩色印刷颜料和塑料制品的着色剂。也用于生产尼龙-4及医药中间体。还可用作试剂。
【用途三】
主要用作喹吖酮类颜料的原料。此种颜料广泛应用于汽车和镀锌铁皮涂料、彩色印刷颜料和塑料制品的着色剂。也用于生产尼龙-4及医药中间体。还可用作试剂。
丁二腈名称
[ CAS 号 ]:
110-61-2
[ 中文名 ]:
丁二腈
[ 英文名 ]:
Succinonitrile
[中文别名 ]:
[英文别名 ]:
- MFCD00001949
- EINECS 203-783-9
- Butanedinitrile
- Ethylene Dicyanide
- Succinonitrile
- Ethylene Cyanide
- Succinonitrilato
- 1,2-Dicyanoethane
丁二腈物理化学性质
[ 密度 ]:
1.0±0.1 g/cm3
[ 沸点 ]:
268.5±13.0 °C at 760 mmHg
[ 熔点 ]:
50-54 °C(lit.)
[ 分子式 ]:
C4H4N2
[ 分子量 ]:
80.088
[ 闪点 ]:
141.1±13.7 °C
[ 精确质量 ]:
80.037445
[ PSA ]:
47.58000
[ LogP ]:
-0.99
[ 外观性状 ]:
近乎于白色至棕色结晶固体
[ 蒸汽压 ]:
0.0±0.5 mmHg at 25°C
[ 折射率 ]:
1.416
[ 储存条件 ]:
库房通风低温干燥,与氧化剂、酸类、食品添加剂分开存放
[ 水溶解性 ]:
slightly soluble
丁二腈MSDS
丁二腈毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WN3850000
- CHEMICAL NAME :
- Succinonitrile
- CAS REGISTRY NUMBER :
- 110-61-2
- BEILSTEIN REFERENCE NO. :
- 1098380
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 14
- MOLECULAR FORMULA :
- C4-H4-N2
- MOLECULAR WEIGHT :
- 80.10
- WISWESSER LINE NOTATION :
- NC2CN
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 450 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985. Volume(issue)/page/year: 2C,4879,1982
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 730 mg/m3/4H
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - acute pulmonary edema
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0570875
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 129 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 57,88,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 63110 ug/kg
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - other changes in urine composition
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 27,1135,1978
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 150 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Gastrointestinal - nausea or vomiting
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 3,77,1897
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 36 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - spastic paralysis with or without sensory change
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 3,77,1897
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Bird - pigeon
- DOSE/DURATION :
- 2200 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Gastrointestinal - nausea or vomiting
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 3,77,1897
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 3,77,1897 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 365 mg/kg
- SEX/DURATION :
- female 8 day(s) after conception
- REFERENCE :
- FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 3,41,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO SUCCINONITRILE-air:10H TWA 6 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5846 No. of Facilities: 44 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 1440 (estimated)
丁二腈安全信息
[ 符号 ]:
GHS07
[ 信号词 ]:
Warning
[ 危害声明 ]:
H302-H315-H319-H335
[ 警示性声明 ]:
P261-P305 + P351 + P338
[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ 危害码 (欧洲) ]:
Xn:Harmful;
[ 风险声明 (欧洲) ]:
R20/21/22;R36/38
[ 安全声明 (欧洲) ]:
S26-S36/37-S45-S36/37/39-S22
[ 危险品运输编码 ]:
3276
[ WGK德国 ]:
3
[ RTECS号 ]:
WN3850000
[ 包装等级 ]:
III
[ 危险类别 ]:
6.1
[ 海关编码 ]:
2926909090
丁二腈合成路线
丁二腈上下游产品
丁二腈上游产品
丁二腈下游产品
丁二腈制备
以丙烯腈为原料，在碱性条件下与氰氢酸反应制得。收率95%以上。也可将氰化钠水溶液加热，滴加1,2-二溴乙烷的乙醇溶液，回流反应35h，可生成丁二腈。
精制方法：将丁二腈进行升华精制。或用丙酮重结晶后进行减压蒸馏，可得高纯度产品。
丁二腈海关
[ 海关编码 ]: 2926909090
[ 中文概述 ]:
2926909090 其他腈基化合物. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
丁二腈文献
Chem. Biol. Interact. 217 , 41-8, (2014)
Graphical abstract Synthesis of new oxazolines (3[4,5-dihydro-1,3-oxazol-2-yl] propanenitriles).
Study of ion transport in lithium perchlorate-succinonitrile plastic crystalline electrolyte via ionic conductivity and in situ cryo-crystallography.J. Phys. Chem. B 113(15) , 5025-31, (2009)
Ion transport mechanism in lithium perchlorate (LiClO(4))-succinonitrile (SN), a prototype of plastic crystalline soft matter electrolyte is discussed in the context of solvent configurational isomeri...
Tetramethyl substitution on succinonitrile confers pentylenetetrazol-like activity and blocks cyanide release in mice.J. Pharmacol. Exp. Ther. 223(3) , 635-41, (1982)
相关化工产品/化学物质：
推荐生产厂家/供应商：
公司名：上海化源世纪贸易有限公司
区域：上海市普陀区
价格：
联系人：徐乾明
产品详情：丁二腈
公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥265.0/100g
￥95.0/25g
联系人：刘佳
产品详情：丁二腈
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥559.0/500g
￥61.0/25g
￥需询单/1g
￥111.0/100g
联系人：阿拉丁
产品详情：丁二腈
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相关化合物
【丁二腈】化源网提供丁二腈CAS号110-61-2，丁二腈MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询丁二腈上化源网，专业又轻松。>>电脑版：丁二腈
标题：丁二腈_MSDS_用途_密度_丁二腈CAS号【110-61-2】_化源网 地址：https://m.chemsrc.com/mip/cas/110-61-2_752239.html