< 生产厂家价格 >

人降钙素基因相关肽(8-37)

人降钙素基因相关肽(8-37)用途

HCGRP-(8-37) 是人降钙素基因相关肽 (hCGRP) 片段,也是 CGRP 受体的拮抗剂。

点击显示

人降钙素基因相关肽(8-37)名称

[ CAS 号 ]:
119911-68-1

[ 中文名 ]:
降钙素基因相关肽片段

[ 英文名 ]:
Calcitonin Gene Related Peptide Fragment 8-37 human

[中文别名 ]:

[英文别名 ]:

FBHuman
CGRP-I 8-37
EINECS 232-693-2
CGRP-I 8-37,HUMAN
MFCD00133153
CYS2-CYS7
HCGRP-(8-37)

人降钙素基因相关肽(8-37)生物活性

[ 描述 ]:

HCGRP-(8-37) 是人降钙素基因相关肽 (hCGRP) 片段,也是 CGRP 受体的拮抗剂。

[ 相关类别 ]:

信号通路 >> G 蛋白偶联受体/G 蛋白 >> CGRP受体

信号通路 >> 神经信号通路 >> CGRP受体

多肽产品

研究领域 >> 心血管疾病

研究领域 >> 代谢疾病

[ 靶点 ]

CGRP receptor[1]

[参考文献]

[1]. Chiba T, et al. Calcitonin gene-related peptide receptor antagonist human CGRP-(8-37). Am J Physiol. 1989 Feb;256(2 Pt 1):E331-5.

[相关活性小分子]

人降钙素基因相关肽(8-37)物理化学性质

[ 密度 ]:
1.46±0.1 g/cm3

[ 分子式 ]:
C₁₃₉H₂₃₀N₄₄O₃₈

[ 分子量 ]:
3125.59000

[ 精确质量 ]:
3123.74000

[ PSA ]:
1339.16000

[ LogP ]:
1.11560

[ 外观性状 ]:
powder

[ 储存条件 ]:
−20°C

人降钙素基因相关肽(8-37)安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

人降钙素基因相关肽(8-37)文献

Calcitonin gene-related peptide stimulates proliferation and osteogenic differentiation of osteoporotic rat-derived bone mesenchymal stem cells.

Mol. Cell Biochem. 402(1-2) , 101-10, (2015)

Osteoporosis, a systemic bone disorder, is prevalent in postmenopausal woman. Bone mesenchymal stem cells (BMSCs), precursors of osteogenic cells, may contribute to prevention or treatment of bone fru...

Intermedin enhances sympathetic outflow via receptor-mediated cAMP/PKA signaling pathway in nucleus tractus solitarii of rats.

Peptides 47 , 1-6, (2013)

Direct administration of intermedin (IMD) into the brain elicits cardiovascular effects different from the systemic administration. Nucleus tractus solitarii (NTS) is an important region for the cardi...

Intermedin in paraventricular nucleus attenuates sympathetic activity and blood pressure via nitric oxide in hypertensive rats.

Hypertension 63(2) , 330-7, (2014)

Intermedin (IMD) is a member of calcitonin/calcitonin gene-related peptide family, which shares the receptor system consisting of calcitonin receptor-like receptor (CRLR) and receptor activity-modifyi...

更多文献