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钆双胺一水物

钆双胺一水物用途

Gadodiamide是造影剂，用于MR中血管成像。

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钆双胺一水物名称

[ CAS 号 ]:
122795-43-1

[ 中文名 ]:
钆双胺一水物

[ 英文名 ]:
Gadodiamide

[中文别名 ]:

钆双胺一水合物

[英文别名 ]:

Gadodiamide hydrate
Omniscan

钆双胺一水物生物活性

[ 描述 ]:

Gadodiamide是造影剂,用于MR中血管成像。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 其他

[参考文献]

[1]. Canavese, C., et al., Gadolinium-associated nephrogenic systemic fibrosis: the need for nephrologists' awareness. J Nephrol, 2008. 21(3): p. 324-36.

[相关活性小分子]

钆双胺一水物物理化学性质

[ 沸点 ]:
769.1ºC at 760mmHg

[ 分子式 ]:
C₁₆H₂₈GdN₅O₉

[ 分子量 ]:
591.67200

[ 闪点 ]:
419ºC

[ 精确质量 ]:
592.11300

[ PSA ]:
156.05000

[ 外观性状 ]:
粉末

[ 储存条件 ]:
-20℃

钆双胺一水物毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LW3937500

CHEMICAL NAME :: Gadolinium, aqua(5,8-bis(carboxymethyl)-11-(2-(methylamino)-2-oxo ethyl)- 3-oxo-2,5,8,11-tetraazatridecan-13-oato(3-))-, hydrate

CAS REGISTRY NUMBER :: 122795-43-1

LAST UPDATED :: 199607

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C16-H28-Gd-N5-O9.xH2-O

MOLECULAR WEIGHT :: 717.88

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

DOSE :: 16269 mg/kg

SEX/DURATION :: female 7-17 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4 per # born alive) Reproductive - Effects on Newborn - biochemical and metabolic

REFERENCE :: TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 14,78,1994