盐酸阿比朵尔
盐酸阿比朵尔用途
盐酸阿比朵尔作用
盐酸阿比朵尔名称
[ CAS 号 ]:
131707-23-8
[ 中文名 ]:
盐酸阿比朵尔
[ 英文名 ]:
Arbidol HCl
[中文别名 ]:
[英文别名 ]:
- Arbidol Hydrochloride
- Arbidol Hydrochloride Hydrate
- arbidol hydrogen chloride
- umifenovir hydrogen chloride
- Arbidol HCl
- MFCD00333871
- Arbidol
- umifenovir hydrochloride
- Arbidol (hydrochloride)
盐酸阿比朵尔生物活性
[ 描述 ]:
[ 相关类别 ]:
[参考文献]
[相关活性小分子]
盐酸阿比朵尔物理化学性质
[ 沸点 ]:
591.8ºC at 760 mmHg
[ 熔点 ]:
133-137ºC
[ 分子式 ]:
C22H26BrClN2O3S
[ 分子量 ]:
513.875
[ 闪点 ]:
311.7℃
[ 精确质量 ]:
512.053589
[ PSA ]:
80.00000
[ LogP ]:
5.97900
[ 外观性状 ]:
白色或灰白色结晶粉末
[ 蒸汽压 ]:
1.34E-14mmHg at 25°C
[ 储存条件 ]:
Hygroscopic, Refrigerator, Under Inert Atmosphere
[ 稳定性 ]:
Hygroscopic
盐酸阿比朵尔MSDS
盐酸阿比朵尔毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NL5998075
- CHEMICAL NAME :
- 1H-Indole-3-carboxylic acid, 6-bromo-4-((dimethylamino)methyl)-5-hydroxy-1-methyl- 2- ((phenylthio)methyl)-, ethyl ester, monohydrochloride, hydrate
- CAS REGISTRY NUMBER :
- 131707-23-8
- LAST UPDATED :
- 199312
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C22-H25-Br-N2-O3-S.Cl-H.H2-O
- MOLECULAR WEIGHT :
- 531.94
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >3 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 17,1079,1992
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 340 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 17,1079,1992
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- >3 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 17,1079,1992
盐酸阿比朵尔安全信息
[ 符号 ]:
GHS07
[ 信号词 ]:
Warning
[ 危害声明 ]:
H315-H319
[ 警示性声明 ]:
P305 + P351 + P338
[ 危害码 (欧洲) ]:
Xi
[ 风险声明 (欧洲) ]:
36/38
[ 安全声明 (欧洲) ]:
26
[ 危险品运输编码 ]:
NONH for all modes of transport
[ 海关编码 ]:
2933990090
盐酸阿比朵尔海关
[ 海关编码 ]: 2933990090
[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
盐酸阿比朵尔文献
Biomed. Khim. 59(3) , 295-304, (2013)
Isatin (indole-dione) is an endogenous indole that exibits a wide range of biological and physiological activity. The influence of isatin derivatives 5-nitroisatin and arbidol (an antiviral preparatat...
Arbidol exhibits strong inhibition towards UDP-glucuronosyltransferase (UGT) 1A9 and 2B7.Pharmazie 68(12) , 945-50, (2013)
The aim of the present study was to investigate arbidol's inhibition towards UDP-glucuronosyltransferase (UGT) 1A9 and 2B7. The nonspecific probe substrate 4-methylumbelliferone (4-MU) and recombinant...
Pharmacokinetics, metabolism, and excretion of the antiviral drug arbidol in humans.Antimicrob. Agents Chemother. 57(4) , 1743-55, (2013)
Arbidol is a broad-spectrum antiviral drug that is used clinically to treat influenza. In this study, the pharmacokinetics, metabolism, and excretion of arbidol were investigated in healthy male Chine...
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公司名:上海源溪生物科技有限公司
区域:上海市浦东新区
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¥需询单/1g
联系人:赖经理
公司名:上海脉铂医药科技有限公司
区域:上海市嘉定区
价格:
¥489.0/10mg
¥2589.0/100mg
¥539.0/1g
¥需询单/1g
联系人:李先生
产品详情:Arbidol HCl
公司名:上海创赛科技有限公司
区域:上海市嘉定区
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¥97.0/200mg
¥247.0/1g
¥913.0/5g
¥3267.0/25g
联系人:夏言
公司名:上海阿拉丁生化科技股份有限公司
区域:上海市浦东新区
价格:
¥246.9/1g
¥80.9/250mg
¥894.9/5g
¥77.9/200mg
联系人:阿拉丁李高志
产品详情:Arbidol HCl
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