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莪术二酮

莪术二酮用途

莪术二酮 (Curdione)是从莪术中分离到的倍半萜类物质,生物活性高,具有抑制血小板聚集、抵抗血栓形成的功效。

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莪术二酮名称

[ CAS 号 ]:
13657-68-6

[ 中文名 ]:
莪二酮

[ 英文名 ]:
Curdione

[中文别名 ]:

[英文别名 ]:

N1432
Curdione
neo-Curdione
Germacr-1(10)-ene-5,8-dione

莪术二酮生物活性

[ 描述 ]:

莪术二酮 (Curdione)是从莪术中分离到的倍半萜类物质,生物活性高,具有抑制血小板聚集、抵抗血栓形成的功效。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 其他

天然产物 >> 萜类化合物和糖苷

[参考文献]

[1]. SI Li, et al. Effect of curdione on hemorheological indexs in rats with blood stasis syndrome. Anhui Medical and Pharmaceutical Journal, 2012-09

[2]. Quan Xia, et al. Inhibition of platelet aggregation by curdione from Curcuma wenyujin essential Oil. Thrombosis Research Volume 130, Issue 3, September 2012, Pages 409–414

[相关活性小分子]

莪术二酮物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
347.6±42.0 °C at 760 mmHg

[ 分子式 ]:
C₁₅H₂₄O₂

[ 分子量 ]:
236.350

[ 闪点 ]:
130.4±24.9 °C

[ 精确质量 ]:
236.177628

[ PSA ]:
34.14000

[ LogP ]:
3.12

[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C

[ 折射率 ]:
1.458

[ 储存条件 ]:
-20°C

莪术二酮毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LY3960000

CHEMICAL NAME :: Germacr-1(10)-ene-5,8-dione

CAS REGISTRY NUMBER :: 13657-68-6

LAST UPDATED :: 199507

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C15-H24-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 414 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85PEAG "Zhongliu Yanjiu" Cancer Review, Yu, R., et al., eds., Shanghai Science/Technology Publisher, Peop. Rep. China, 1994 Volume(issue)/page/year: -,178,1994

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莪术二酮安全信息

[ 海关编码 ]:
29143990