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1,3-二氯丙烷

1,3-二氯丙烷用途

【用途一】
用于有机合成
【用途二】
用作溶剂和洗涤剂及色谱分析标准物质
【用途三】
用作有机合成中间体，溶剂。

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1,3-二氯丙烷名称

[ CAS 号 ]:
142-28-9

[ 中文名 ]:
1,3-二氯丙烷

[ 英文名 ]:
1,3-Dichloropropane

[中文别名 ]:

[英文别名 ]:

Propandiyldichlorid
1,3-dichloropropan-2-one O-benzyloxime
MFCD00000999
1,3-dichloro-2-propanone O-benzyloxime
EINECS 205-531-3
1,3-Dichlor-propan
1,3-dichloro-propane
Propane, 1,3-dichloro-
1,3-Dichloropropane
Trimethylene dichloride

1,3-二氯丙烷物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
120.4±0.0 °C at 760 mmHg

[ 熔点 ]:
−99 °C(lit.)

[ 分子式 ]:
C₃H₆Cl₂

[ 分子量 ]:
112.986

[ 闪点 ]:
32.2±0.0 °C

[ 精确质量 ]:
111.984657

[ LogP ]:
2.00

[ 外观性状 ]:
透明无色液体

[ 蒸汽压 ]:
18.3±0.2 mmHg at 25°C

[ 折射率 ]:
1.422

[ 储存条件 ]:
库房通风低温干燥,与氧化剂分开存放

[ 水溶解性 ]:
0.8 g/L (20 ºC)

1,3-二氯丙烷MSDS

1,3-二氯丙烷毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TX9660000

CHEMICAL NAME :: Propane, 1,3-dichloro-

CAS REGISTRY NUMBER :: 142-28-9

LAST UPDATED :: 199712

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C3-H6-Cl2

MOLECULAR WEIGHT :: 112.99

WISWESSER LINE NOTATION :: G3G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3600 mg/kg

TOXIC EFFECTS :: Gastrointestinal - ulceration or bleeding from stomach Gastrointestinal - ulceration or bleeding from small intestine

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - chronic pulmonary edema Liver - other changes Blood - hemorrhage

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8400 mg/kg/14D-I

TOXIC EFFECTS :: Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Biochemical - Metabolism (Intermediary) - other proteins

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 72 gm/kg/90D-I

TOXIC EFFECTS :: Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 6600 umol/L

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 9,401,1987

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1,3-二氯丙烷安全信息

[ 符号 ]:

GHS02, GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H226-H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
F:Flammable

[ 风险声明 (欧洲) ]:
R11;R20/22

[ 安全声明 (欧洲) ]:
S9-S16-S29-S33-S24-S61-S26-S45-S36/37-S7

[ 危险品运输编码 ]:
UN 1993 3/PG 2

[ WGK德国 ]:
2

[ RTECS号 ]:
TX9660000

[ 包装等级 ]:
II

[ 危险类别 ]:
3

[ 海关编码 ]:
2903199000

1,3-二氯丙烷合成路线

1,3-二氯丙烷上下游产品

1,3-二氯丙烷上游产品

1,3-二氯丙烷下游产品

1,3-二氯丙烷制备

由丙二醇与盐酸作用而得。

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1,3-二氯丙烷海关

[ 海关编码 ]: 2903199000

[ 中文概述 ]:
2903199000 其他无环烃的饱和氯化衍生物。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2903199000 other saturated chlorinated derivatives of acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

1,3-二氯丙烷文献

Metabolism and mutagenicity of source water contaminants 1,3-dichloropropane and 2,2-dichloropropane.

Drug Metab. Dispos. 32(1) , 123-31, (2004)

Cytochrome P450-dependent oxidation and glutathione (GSH)-dependent conjugation are the primary routes of metabolism of haloalkanes. Using rat liver microsomes and cytosol, we investigated the metabol...

1,3-Dichloropropene (technical grade).

Rep. Carcinog. 10 , 91-3, (2002)

Biological effect monitoring.

Arch. Toxicol. Suppl. 15 , 268-77, (1992)

更多文献

1,3-二氯丙烷

1,3-二氯丙烷用途

1,3-二氯丙烷名称

1,3-二氯丙烷物理化学性质

1,3-二氯丙烷MSDS

详细MSDS(安全技术说明书)

1,3-二氯丙烷毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

1,3-二氯丙烷安全信息

1,3-二氯丙烷合成路线

详细合成路线

1,3-二氯丙烷上下游产品

1,3-二氯丙烷上游产品

1,3-二氯丙烷下游产品

1,3-二氯丙烷制备

1,3-二氯丙烷海关

1,3-二氯丙烷文献

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