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Zinquin

Zinquin用途

Zinquin 是一种荧光传感器,可用于观察活性锌离子。

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Zinquin名称

[ CAS 号 ]:
151606-29-0

[ 中文名 ]:
Zinquin

[ 英文名 ]:
Zinquin

[英文别名 ]:

zinquin acid
Zinquin
Zinquin,Free Acid

Zinquin生物活性

[ 描述 ]:

Zinquin 是一种荧光传感器,可用于观察活性锌离子。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

染料试剂

研究领域 >> 其他

[参考文献]

[1]. Nowakowski A, et al. Sensor specific imaging of proteomic Zn2+ with zinquin and TSQ after cellular exposure to N-ethylmaleimide. Metallomics. 2012 May;4(5):448-56.

[相关活性小分子]

Zinquin物理化学性质

[ 密度 ]:
1.412g/cm3

[ 沸点 ]:
608ºC at 760 mmHg

[ 熔点 ]:
112-114ºC

[ 分子式 ]:
C₁₉H₁₈N₂O₅S

[ 分子量 ]:
386.42

[ PSA ]:
102.97000

[ LogP ]:
4.74810

[ 蒸汽压 ]:
1.23E-15mmHg at 25°C

[ 折射率 ]:
1.661

[ 储存条件 ]:
-20°C，密闭，干燥

Zinquin安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

Zinquin合成路线

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Zinquin文献

Vimentin filament organization and stress sensing depend on its single cysteine residue and zinc binding.

Nat. Commun. 6 , 7287, (2015)

The vimentin filament network plays a key role in cell architecture and signalling, as well as in epithelial-mesenchymal transition. Vimentin C328 is targeted by various oxidative modifications, but i...

Sensor specific imaging of proteomic Zn2+ with zinquin and TSQ after cellular exposure to N-ethylmaleimide.

Metallomics 4(5) , 448-56, (2012)

The impact of the thiol binding reagent N-ethylmaleimide (NEM) on proteomic Zn(2+) availability was investigated in rat glioma cells. Zinquin (ZQ) or TSQ, two related fluorescent sensors, were used to...

3,3'-Dihydroxyisorenieratene prevents UV-induced formation of reactive oxygen species and the release of protein-bound zinc ions in human skin fibroblasts.

Mol. Nutr. Food. Res. 54(2) , 285-91, (2010)

3,3'-Dihydroxyisorenieratene (DHIR) is a structurally unusual carotenoid exhibiting bifunctional antioxidant properties. It is synthesized by Brevibacterium linens, used in dairy industry for the prod...

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