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1-氨基芘

1-氨基芘名称

[ CAS 号 ]:
1606-67-3

[ 中文名 ]:
1-氨基芘

[ 英文名 ]:
aminopyrene

[中文别名 ]:

[英文别名 ]:

aminopyrene
Pyren-1-amine
pyrenylamine
Pyrene,amino
EINECS 216-521-3
1-Pyrenamine
Pyren-1-amin
1-aminopyrene
aminoantipyrene
pyren-1-ylamine

1-氨基芘物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
440.8±14.0 °C at 760 mmHg

[ 熔点 ]:
115-117 °C(lit.)

[ 分子式 ]:
C₁₆H₁₁N

[ 分子量 ]:
217.265

[ 闪点 ]:
246.2±15.4 °C

[ 精确质量 ]:
217.089142

[ PSA ]:
26.02000

[ LogP ]:
3.89

[ 外观性状 ]:
黄色-绿色粉末

[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C

[ 折射率 ]:
1.905

[ 储存条件 ]:
存放于惰性气体之中;避免空气

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents.

[ 水溶解性 ]:
水溶性：不溶；可溶于：乙醇,乙醚,苯

1-氨基芘MSDS

1-氨基芘毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UR2275000

CHEMICAL NAME :: 1-Pyrenamine

CAS REGISTRY NUMBER :: 1606-67-3

BEILSTEIN REFERENCE NO. :: 1875737

LAST UPDATED :: 199701

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C16-H11-N

MOLECULAR WEIGHT :: 217.28

WISWESSER LINE NOTATION :: L666 B6 2AB PJ GZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1070 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >1 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: DNA repair

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 40 mg/L

REFERENCE :: MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 2,23,1987

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1-氨基芘安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H312

[ 警示性声明 ]:
P280

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R21/22;R40

[ 安全声明 (欧洲) ]:
S45-S36/37

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
UR2275000

[ 海关编码 ]:
2921499090

1-氨基芘合成路线

1-氨基芘上下游产品

1-氨基芘上游产品

1-氨基芘下游产品

1-氨基芘海关

[ 海关编码 ]: 2921499090

[ 中文概述 ]:
2921499090 其他芳香单胺及衍生物及它们的盐. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

1-氨基芘文献

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Nat. Commun. 6 , 7040, (2015)

Electrochemical energy-storage devices have the potential to be clean and efficient, but their current cost and performance limit their use in numerous transportation and stationary applications. Many...

A method for high-throughput, sensitive analysis of IgG Fc and Fab glycosylation by capillary electrophoresis.

J. Immunol. Methods 417 , 34-44, (2015)

The N-glycan of the IgG constant region (Fc) plays a central role in tuning and directing multiple antibody functions in vivo, including antibody-dependent cellular cytotoxicity, complement deposition...

Biopartitioning micellar chromatography to predict mutagenicity of aromatic amines.

Eur. J. Med. Chem. 42 , 1396-402, (2007)

Mutagenicity is a toxicity endpoint associated with the chronic exposure to chemicals. Aromatic amines have considerable industrial and environmental importance due to their widespread use in industry...

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