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血卟啉二盐酸盐

血卟啉二盐酸盐用途

Hematoporphyrin二盐酸盐是一种血红素结合蛋白亲和色谱底物。

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血卟啉二盐酸盐名称

[ CAS 号 ]:
17696-69-4

[ 中文名 ]:
血卟啉二盐酸盐

[ 英文名 ]:
Hematoporphyrin (dihydrochloride)

[中文别名 ]:

[英文别名 ]:

MFCD00013470
HEMATOPORPHYRIN DIHYDROCHLORIDE
EINECS 241-699-4
HAEMATOPORPHYRIN DIHYDROCHLORIDE
Hematoporphyrin (dihydrochloride)

血卟啉二盐酸盐生物活性

[ 描述 ]:

Hematoporphyrin二盐酸盐是一种血红素结合蛋白亲和色谱底物。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 其他

[参考文献]

[1]. Olsen, K.W., Affinity chromatography of heme-binding proteins: synthesis and characterization of hematin- and hematoporphyrin-agarose. Methods Enzymol, 1986. 123: p. 324-31.

[相关活性小分子]

血卟啉二盐酸盐物理化学性质

[ 沸点 ]:
1192.7ºC at 760 mmHg

[ 分子式 ]:
C₃₄H₄₀Cl₂N₄O₆

[ 分子量 ]:
671.611

[ 闪点 ]:
675.1ºC

[ 精确质量 ]:
670.232483

[ PSA ]:
171.36000

[ LogP ]:
4.24970

[ 外观性状 ]:
紫色固体

[ 蒸汽压 ]:
0mmHg at 25°C

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
Insoluble in water. Soluble in pyridine (5%).

血卟啉二盐酸盐MSDS

详细MSDS(安全技术说明书)

血卟啉二盐酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TS5505000

CHEMICAL NAME :: 2,18-Porphinedipropionic acid, 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-, dihydrochloride

CAS REGISTRY NUMBER :: 17696-69-4

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C34-H38-N4-O6.2Cl-H

MOLECULAR WEIGHT :: 671.68

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 117,145,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 278 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - changes in motor activity (specific assay) Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 117,145,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 117,145,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 169 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - changes in motor activity (specific assay) Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 117,145,1978