新橙皮苷二氢查尔酮

Neohesperidin dihydrochalcone是一种合成的糖苷查耳酮,作为低热量人造甜味剂添加到各种食品和饮料中。

[ 描述 ]:

[ 相关类别 ]:

[体外研究]

[体内研究]

[细胞实验]

[动物实验]

[参考文献]

[相关活性小分子]

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
927.1±65.0 °C at 760 mmHg

[ 熔点 ]:
156-158 °C(lit.)

[ 分子式 ]:
C₂₈H₃₆O₁₅

[ 分子量 ]:
612.576

[ 闪点 ]:
302.6±27.8 °C

[ 精确质量 ]:
612.205444

[ PSA ]:
245.29000

[ LogP ]:
3.09

[ 外观性状 ]:
白色粉末

[ 蒸汽压 ]:
0.0±0.3 mmHg at 25°C

[ 折射率 ]:
1.684

[ 储存条件 ]:
−20°C

[ 水溶解性 ]:
Insoluble

详细MSDS(安全技术说明书)

CHEMICAL IDENTIFICATION

RTECS NUMBER :

LZ5785000

CHEMICAL NAME :

Glucopyranoside, 3,5-dihydroxy-4-(3-hydroxy-4-methoxyhydrocinnamoyl)ph enyl- 2-O-(6-deoxy-alpha-L-mannopyranosyl)-, beta-D-

CAS REGISTRY NUMBER :

20702-77-6

LAST UPDATED :

199312

DATA ITEMS CITED :

3

MOLECULAR FORMULA :

C28-H36-O15

MOLECULAR WEIGHT :

612.64

WISWESSER LINE NOTATION :

T6OTJ B1 CQ DQ EQ FO- CT6OTJ BOR CQ EQ DV2R CQ DO1&& DQ EQ F1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

365 mg/kg/13W-C

TOXIC EFFECTS :

Gastrointestinal - other changes Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic - weight loss or decreased weight gain

MUTATION DATA

TEST SYSTEM :

Rodent - mouse

DOSE/DURATION :

200 mg/kg

REFERENCE :

MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 89,69,1981

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
C

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
LZ5785000

[ 海关编码 ]:
2932999099

新橙皮苷二氢查尔酮上游产品

新橙皮苷二氢查尔酮下游产品

由柑橘类的酸橙(Citrus aurantium英文名Seville orange)的皮用水提取得新橙皮苷，然后根据在水中溶解度的不同分别除去其中的柚苷和橙皮素。再将其溶于KOH液中，在钯一碳催化剂存在下，加压氢化，然后过滤、酸化、低温结晶并重结晶而得。

[ 海关编码 ]: 2932999099

[ 中文概述 ]:
2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Protective effects of neohesperidin dihydrochalcone against carbon tetrachloride-induced oxidative damage in vivo and in vitro.

Chem. Biol. Interact. 213 , 51-9, (2014)

The purpose of this study was to investigate the possible hepatoprotective effects of neohesperidin dihydrochalcone (NHDC) on carbon tetrachloride (CCl4)-induced acute oxidative injury in vivo and in ...

Determination of high-intensity sweeteners in river water and wastewater by solid-phase extraction and liquid chromatography-tandem mass spectrometry.

J. Chromatogr. A. 1393 , 106-14, (2015)

High-intensity sweeteners have been suggested as potential organic contaminants due to their widespread use in food, drugs and sanitary products. As a consequence, they are introduced into the environ...

Neohesperidin dihydrochalcone: presentation of a small molecule activator of mammalian alpha-amylase as an allosteric effector.

FEBS Lett. 587(6) , 652-8, (2013)

Flavonoids and their precursor trans-chalcone have been reported as inhibitors of mammalian alpha-amylase. With regard to this background, neohesperidin dihydrochalcone (NHDC) effect was investigated ...

更多文献

公司名：上海化源世纪贸易有限公司

区域：上海市普陀区

价格：

联系人：徐经理

产品详情：新橙皮苷二氢查尔酮

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公司名：南通润丰石油化工有限公司

区域：南通市崇川区

价格：
￥需询单/1kg ￥需询单/1ton

联系人：曹经理

产品详情：新橙皮甙二氢查尔酮

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公司名：云南西力生物技术股份有限公司

区域：昆明市盘龙区

价格：
￥需询单/5mg

联系人：郑雪平

产品详情：新橙皮苷二氢查尔酮

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公司名：上海吉至生化科技有限公司

区域：上海市奉贤区

价格：
￥278.0/20mg ￥108.0/1g ￥278.0/5g

联系人：刘佳

产品详情：新橙皮苷二氢查尔酮

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公司名：上海脉铂医药科技有限公司

区域：上海市嘉定区

价格：
￥439.0/100mg ￥869.0/1g ￥639.0/500mg ￥1799.0/500g

联系人：李先生

产品详情：Neosperidin dihydrochalcone

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