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地弗地衣酸

地弗地衣酸用途

Diffractaic acid 是 U. longissimi 的主要成分,在各种疾病研究中可作为有效的促凋亡剂。Diffractaic acid 还具有止痛和解热效果。

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地弗地衣酸名称

[ CAS 号 ]:
436-32-8

[ 中文名 ]:
地弗地衣酸

[ 英文名 ]:
Diffractaic acid

[英文别名 ]:

diffractic acid
diffractaic acid
Diffractasaeure
Dirbizomic acid
DIFFRACTOIC ACID
Dirhizomic acid
DIFFRACTANIC ACID
diffratic acid

地弗地衣酸生物活性

[ 描述 ]:

Diffractaic acid 是 U. longissimi 的主要成分,在各种疾病研究中可作为有效的促凋亡剂。Diffractaic acid 还具有止痛和解热效果。

[ 相关类别 ]:

信号通路 >> 细胞凋亡 >> 细胞凋亡

研究领域 >> 癌症

研究领域 >> 炎症/免疫

[体内研究]

通过醋酸致小鼠扭体法和尾压法,证明了衍射酸具有镇痛作用[2]。

[参考文献]

[1]. Fehmi Odabasoglu, et al. Diffractaic acid, a novel proapoptotic agent, induces with olive oil both apoptosis and antioxidative systems in Ti-implanted rabbits. Eur J Pharmacol. 2012 Jan 15;674(2-3):171-8.

[2]. E Okuyama, et al. Usnic acid and diffractaic acid as analgesic and antipyretic components of Usnea diffracta. Planta Med. 1995 Apr;61(2):113-5.

地弗地衣酸物理化学性质

[ 密度 ]:
1.26g/cm3

[ 沸点 ]:
604.9ºC at 760mmHg

[ 分子式 ]:
C₂₀H₂₂O₇

[ 分子量 ]:
374.38400

[ 闪点 ]:
214.2ºC

[ 精确质量 ]:
374.13700

[ PSA ]:
102.29000

[ LogP ]:
3.56040

[ 蒸汽压 ]:
1.74E-15mmHg at 25°C

[ 折射率 ]:
1.583

[ 储存条件 ]:
2-8℃

地弗地衣酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VH3708850

CHEMICAL NAME :: beta-Resorcylic acid, 3,6-dimethyl-, 4-(2,4-dimethoxy-3,6-dimethylbenzoate)

CAS REGISTRY NUMBER :: 436-32-8

BEILSTEIN REFERENCE NO. :: 2915070

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C20-H22-O7

MOLECULAR WEIGHT :: 374.42

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 962 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 5,335,1981

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地弗地衣酸安全信息

[ 海关编码 ]:
2918990090

地弗地衣酸合成路线

详细合成路线

地弗地衣酸上下游产品

地弗地衣酸上游产品

地弗地衣酸下游产品

地弗地衣酸海关

[ 海关编码 ]: 2918990090

[ 中文概述 ]:
2918990090. 其他含其他附加含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%