地弗地衣酸

• 常用名: 地弗地衣酸
• 英文名: Diffractaic acid
• CAS号: 436-32-8
• 分子量: 374.38400
• 密度: 1.26g/cm3
• 沸点: 604.9ºC at 760mmHg
• 分子式: C₂₀H₂₂O₇
• 熔点: N/A
• 闪点: 214.2ºC

地弗地衣酸用途

Diffractaic acid 是 U. longissimi 的主要成分,在各种疾病研究中可作为有效的促凋亡剂。Diffractaic acid 还具有止痛和解热效果。

地弗地衣酸名称

• 中文名: 地弗地衣酸
• 英文名: 4-(2,4-dimethoxy-3,6-dimethylbenzoyl)oxy-2-hydroxy-3,6-dimethylbenzoic acid

地弗地衣酸生物活性

• 描述: Diffractaic acid 是 U. longissimi 的主要成分,在各种疾病研究中可作为有效的促凋亡剂。Diffractaic acid 还具有止痛和解热效果。
• 相关类别:
  信号通路 >> 细胞凋亡 >> 细胞凋亡
  研究领域 >> 癌症
  研究领域 >> 炎症/免疫
• 体内研究: 通过醋酸致小鼠扭体法和尾压法,证明了衍射酸具有镇痛作用[2]。
• 参考文献:

  [1]. Fehmi Odabasoglu, et al. Diffractaic acid, a novel proapoptotic agent, induces with olive oil both apoptosis and antioxidative systems in Ti-implanted rabbits. Eur J Pharmacol. 2012 Jan 15;674(2-3):171-8.

  [2]. E Okuyama, et al. Usnic acid and diffractaic acid as analgesic and antipyretic components of Usnea diffracta. Planta Med. 1995 Apr;61(2):113-5.

地弗地衣酸物理化学性质

• 密度: 1.26g/cm3
• 沸点: 604.9ºC at 760mmHg
• 分子式: C₂₀H₂₂O₇
• 分子量: 374.38400
• 闪点: 214.2ºC
• 精确质量: 374.13700
• PSA: 102.29000
• LogP: 3.56040
• InChIKey: MIJKZXWOOXIEEU-UHFFFAOYSA-N
• SMILES: COc1cc(C)c(C(=O)Oc2cc(C)c(C(=O)O)c(O)c2C)c(OC)c1C
• 蒸汽压: 1.74E-15mmHg at 25°C
• 折射率: 1.583
• 储存条件: 2-8℃

地弗地衣酸毒性和生态

地弗地衣酸安全信息

• 海关编码: 2918990090

地弗地衣酸海关

• 海关编码: 2918990090
• 中文概述: 2918990090. 其他含其他附加含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

地弗地衣酸靶点实验

查看更多实验

实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：ERK5 transcriptional activity HTS 来源：24565 靶标：N/A External Id：ERK5 transcriptional activity-HTS

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect... 来源：Broad Institute 靶标：N/A External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

实验名称：EZH2/PRC2 methyltransferase inhibitors Measured in Biochemical System Using Plate Rea... 来源：Broad Institute 靶标：histone-lysine N-methyltransferase EZH2 isoform a [Homo sapiens] External Id：2125-01_Inhibitor_SinglePoint_HTS_Activity

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地弗地衣酸英文别名

• 2,4-dimethoxy-3,6-dimethylbenzoic acid 4'-carboxy-3'-hydroxy-2',5'-dimethylphenyl ester
• diffractic acid
• diffractaic acid
• Diffractasaeure
• Dirbizomic acid
• DIFFRACTOIC ACID
• Dirhizomic acid
• DIFFRACTANIC ACID
• diffratic acid