20-羟基蜕皮甾酮
20-羟基蜕皮甾酮用途
20-羟基蜕皮甾酮名称
[ CAS 号 ]:
5289-74-7
[ 中文名 ]:
蜕皮激素
[ 英文名 ]:
Hydroxyecdysone
[中文别名 ]:
[英文别名 ]:
- CRUSTECDYSONE
- 20-hydroxyecdysone
- MFCD00036740
- β-ecdysone
- Hydroxyecdysone
- b-Ecdysone
- Isoinokosterone
- Commisterone
- Ecdysterone
20-羟基蜕皮甾酮生物活性
[ 描述 ]:
[ 相关类别 ]:
[参考文献]
20-羟基蜕皮甾酮物理化学性质
[ 密度 ]:
1.3±0.1 g/cm3
[ 沸点 ]:
702.1±60.0 °C at 760 mmHg
[ 熔点 ]:
242-244 °C
[ 分子式 ]:
C27H44O7
[ 分子量 ]:
480.634
[ 闪点 ]:
392.4±29.4 °C
[ 精确质量 ]:
480.308716
[ PSA ]:
138.45000
[ LogP ]:
-0.53
[ 外观性状 ]:
淡黄色黄色细粉末
[ 蒸汽压 ]:
0.0±5.0 mmHg at 25°C
[ 折射率 ]:
1.597
[ 储存条件 ]:
2-8°C
[ 水溶解性 ]:
alcohol: soluble
20-羟基蜕皮甾酮毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- FZ8060000
- CHEMICAL NAME :
- 5-beta-Cholest-7-en-6-one, 2-beta,3-beta,14,20,22,25-hexahydroxy-, (22R)-
- CAS REGISTRY NUMBER :
- 5289-74-7
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C27-H44-O7
- MOLECULAR WEIGHT :
- 480.71
- WISWESSER LINE NOTATION :
- L E5 B666 LV JUTJ A1 E1 FXQ1&YQ2XQ1&1 IQ OQ PQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >9 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 350 ug/kg
- SEX/DURATION :
- male 7 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands
- TYPE OF TEST :
- Cytogenetic analysis
- TYPE OF TEST :
- Cytogenetic analysis
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 100 nmol/L
- REFERENCE :
- ENZYAS Enzymologia. (The Hague, Netherlands) V.1-43, 1936-72. Volume(issue)/page/year: 41,183,1971
20-羟基蜕皮甾酮安全信息
[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ 危害码 (欧洲) ]:
Xi
[ 风险声明 (欧洲) ]:
R36/37/38
[ 安全声明 (欧洲) ]:
S22-S24/25
[ 危险品运输编码 ]:
NONH for all modes of transport
[ WGK德国 ]:
2
[ RTECS号 ]:
FZ8060000
[ 包装等级 ]:
II; III
[ 危险类别 ]:
4.1
[ 海关编码 ]:
2937290090
20-羟基蜕皮甾酮制备
可从昆虫、甲壳类动物和植物中分离出这类生理活性物质。已能人工化学合成,但由于化学结构复杂,合成工序很多。
20-羟基蜕皮甾酮海关
[ 海关编码 ]: 2937290090
20-羟基蜕皮甾酮文献
Insect Biochem. Mol. Biol. 63 , 23-33, (2015)
Our previous results revealed that RNA interference-aided knockdown of Leptinotarsa decemlineata FTZ-F1 (LdFTZ-F1) reduced 20E titer, and impaired pupation. In this study, we characterized a putative ...
Identification of two juvenile hormone inducible transcription factors from the silkworm, Bombyx mori.J. Insect Physiol. 80 , 31-41, (2015)
Juvenile hormone (JH) regulates many physiological processes in insects. However, the signal cascades in which JH is active have not yet been fully elucidated, particularly in comparison to another ma...
A view through a chromatin loop: insights into the ecdysone activation of early genes in Drosophila.Nucleic Acids Res. 42(16) , 10409-24, (2014)
The early genes are a key group of ecdysone targets that function at the top of the signaling hierarchy. In the presence of ecdysone, early genes exhibit a highly characteristic rapid and powerful ind...
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公司名:上海化源世纪贸易有限公司
区域:上海市普陀区
价格:
联系人:徐乾明
产品详情:蜕皮激素(β-蜕皮甾酮)
公司名:上海吉至生化科技有限公司
区域:上海市奉贤区
价格:
¥388.0/20mg
联系人:刘佳
产品详情:蜕皮激素
公司名:上海脉铂医药科技有限公司
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价格:
¥1189.0/20mg
¥739.0/1g
¥需询单/1g
¥需询单/1g
联系人:李先生
产品详情:Ecdysterone
公司名:上海阿拉丁生化科技股份有限公司
区域:上海市浦东新区
价格:
¥592.9/100mg
¥403.9/100mg
¥161.9/25mg
¥167.9/20mg
联系人:阿拉丁
产品详情:蜕皮激素
公司名:上海创赛科技有限公司
区域:上海市嘉定区
价格:
¥175.0/20mg
¥653.0/100mg
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¥978.0/500mg
联系人:夏言
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相关化合物
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