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DL-2-氨基己二酸

DL-2-氨基己二酸用途

Aminoadipic acid是赖氨酸和糖嘌呤代谢的中间体。

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DL-2-氨基己二酸名称

[ CAS 号 ]:
542-32-5

[ 中文名 ]:
DL-a-氨基己二酸

[ 英文名 ]:
α-Aminoadipic acid

[中文别名 ]:

[英文别名 ]:

2-Aminohexanedioic acid
2-aminoadipic acid
AAD
DL-2-Aminohexanedioic acid
Hexanedioic acid, 2-amino-, (2R)-
D-2-Aminoadipic Acid
Hexanedioic acid, 2-amino-
α-Amino-adipic acid
.α.-Aminoadipic acid
UNII:1K7B1OED4N

DL-2-氨基己二酸生物活性

[ 描述 ]:

Aminoadipic acid是赖氨酸和糖嘌呤代谢的中间体。

[ 相关类别 ]:

天然产物 >> 酸和醛

研究领域 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Wang TJ, et al. 2-Aminoadipic acid is a biomarker for diabetes risk. J Clin Invest. 2013 Oct;123(10):4309-17.

[2]. Wang X, et al. α-Aminoadipic acid protects against retinal disruption through attenuating Müller cell gliosis in a rat model of acute ocular hypertension. Drug Des Devel Ther. 2016 Oct 20;10:3449-3457.

[相关活性小分子]

DL-2-氨基己二酸物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
364.0±32.0 °C at 760 mmHg

[ 熔点 ]:
196-198ºC

[ 分子式 ]:
C₆H₁₁NO₄

[ 分子量 ]:
161.156

[ 闪点 ]:
173.9±25.1 °C

[ 精确质量 ]:
161.068802

[ PSA ]:
100.62000

[ LogP ]:
-0.54

[ 外观性状 ]:
结晶

[ 蒸汽压 ]:
0.0±1.7 mmHg at 25°C

[ 折射率 ]:
1.515

[ 储存条件 ]:
2-8°C

DL-2-氨基己二酸MSDS

DL-2-氨基己二酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MO1852000

CHEMICAL NAME :: Hexanedioic acid, 2-amino-

CAS REGISTRY NUMBER :: 542-32-5

BEILSTEIN REFERENCE NO. :: 1773077

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C6-H11-N-O4

MOLECULAR WEIGHT :: 161.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 5,108,1960

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DL-2-氨基己二酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H317

[ 警示性声明 ]:
P280

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
MO1852000

[ 海关编码 ]:
2922499990

DL-2-氨基己二酸合成路线

DL-2-氨基己二酸上下游产品

DL-2-氨基己二酸上游产品

DL-2-氨基己二酸下游产品

DL-2-氨基己二酸海关

[ 海关编码 ]: 2922499990

[ 中文概述 ]:
2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

DL-2-氨基己二酸文献

Impact of gluconic fermentation of strawberry using acetic acid bacteria on amino acids and biogenic amines profile.

Food Chem. 178 , 221-8, (2015)

This paper studies the amino acid profile of beverages obtained through the fermentation of strawberry purée by a surface culture using three strains belonging to different acetic acid bacteria specie...

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression.

Nature 457(7231) , 910-4, (2009)

Multiple, complex molecular events characterize cancer development and progression. Deciphering the molecular networks that distinguish organ-confined disease from metastatic disease may lead to the i...

Comparative metabolomics analysis on invigorating blood circulation for herb pair Gui-Hong by ultra-high-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry and pattern recognition approach.

J. Pharm. Biomed. Anal. 107 , 456-63, (2015)

The compatibility of Angelicae Sinensis Radix (Danggui, DG) and Flos Carthami (Honghua, HH), a famous herb pair Gui-Hong (GH), can produce synergistic and promoting blood effects. Although some physio...

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