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肌酸

肌酸用途

Creatine,一种内源性氨基酸代谢物,在细胞能量中发挥重要作用,尤其是在肌肉和大脑中。

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肌酸名称

[ CAS 号 ]:
57-00-1

[ 中文名 ]:
肌酸

[ 英文名 ]:
Creatine

[中文别名 ]:

[英文别名 ]:

N-AMIDINOSARCOSIN
[[Amino(imino)methyl](methyl)amino]acetic acid
Glycine, N-(aminoiminomethyl)-N-methyl-
glycine, N-[(E)-aminoiminomethyl]-N-methyl-
Creatin
Creatine
CREATINE(P)
2-(1-methylguanidino)acetic acid
Kreatin
Krebiozon

肌酸生物活性

[ 描述 ]:

Creatine,一种内源性氨基酸代谢物,在细胞能量中发挥重要作用,尤其是在肌肉和大脑中。

[ 相关类别 ]:

天然产物 >> 其他

研究领域 >> 代谢疾病

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Nouioua S, et al. Creatine deficiency syndrome. A treatable myopathy due to arginine-glycine amidinotransferase (AGAT) deficiency. Neuromuscul Disord. 2013 Aug;23(8):670-4.

[相关活性小分子]

肌酸物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
271.6±42.0 °C at 760 mmHg

[ 熔点 ]:
~295 °C (dec.)

[ 分子式 ]:
C₄H₉N₃O₂

[ 分子量 ]:
131.133

[ 闪点 ]:
118.1±27.9 °C

[ 精确质量 ]:
131.069473

[ PSA ]:
90.41000

[ LogP ]:
-1.88

[ 外观性状 ]:
淡黄色的液体

[ 蒸汽压 ]:
0.0±1.2 mmHg at 25°C

[ 折射率 ]:
1.552

[ 储存条件 ]:
Store at RT.

[ 水溶解性 ]:
水溶性：微溶；不溶：乙醚

肌酸MSDS

肌酸安全信息

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2925290090

肌酸合成路线

肌酸上下游产品

肌酸上游产品

肌酸下游产品

肌酸海关

[ 海关编码 ]: 2925290090

[ 中文概述 ]:
2925290090 其他亚胺及其衍生物，以及它们的盐。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

肌酸文献

Suramin inhibits Hsp104 ATPase and disaggregase activity.

PLoS ONE 9(10) , e110115, (2014)

Hsp104 is a hexameric AAA+ protein that utilizes energy from ATP hydrolysis to dissolve disordered protein aggregates as well as amyloid fibers. Interestingly, Hsp104 orthologues are found in all king...

BRF1 mutations alter RNA polymerase III-dependent transcription and cause neurodevelopmental anomalies.

Genome Res. 25(2) , 155-66, (2015)

RNA polymerase III (Pol III) synthesizes tRNAs and other small noncoding RNAs to regulate protein synthesis. Dysregulation of Pol III transcription has been linked to cancer, and germline mutations in...

Propofol increases morbidity and mortality in a rat model of sepsis.

Crit. Care 19 , 45, (2015)

Severe sepsis is associated with approximately 50% mortality and accounts for tremendous healthcare costs. Most patients require ventilatory support and propofol is commonly used to sedate mechanicall...

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肌酸

肌酸用途

肌酸名称

肌酸生物活性

肌酸物理化学性质

肌酸MSDS

详细MSDS(安全技术说明书)

肌酸安全信息

肌酸合成路线

详细合成路线

肌酸上下游产品

肌酸上游产品

肌酸下游产品

肌酸海关

肌酸文献

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