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乙酸胍

乙酸胍用途

2-Guanidinoacetic acid 是肌酸的前体,可以成为食用精氨酸的替代物,也能够为鸟类的体内平衡提供能量。

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乙酸胍名称

[ CAS 号 ]:
352-97-6

[ 中文名 ]:
乙酸胍

[ 英文名 ]:
2-Guanidinoacetic acid

[中文别名 ]:

[英文别名 ]:

Guanidinoacetic acid
Acide carbamimidamidoacétique
Guanyl glycine
Guanidineacetic acid
[(aminoiminomethyl)amino]-Acetic acid
(carboxymethyl)-Guanidine
Betasyamine
α-Guanidinoacetic acid
N-Amidinoglycine
Guanidylacetic acid

乙酸胍生物活性

[ 描述 ]:

2-Guanidinoacetic acid 是肌酸的前体,可以成为食用精氨酸的替代物,也能够为鸟类的体内平衡提供能量。

[ 相关类别 ]:

天然产物 >> 其他

研究领域 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Dilger RN, et al. Dietary guanidino acetic acid is an efficacious replacement for arginine for young chicks. Poult Sci. 2013 Jan;92(1):171-7.

[相关活性小分子]

乙酸胍物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
294.2±42.0 °C at 760 mmHg

[ 熔点 ]:
300 °C(lit.)

[ 分子式 ]:
C₃H₇N₃O₂

[ 分子量 ]:
117.107

[ 闪点 ]:
131.7±27.9 °C

[ 精确质量 ]:
117.053825

[ PSA ]:
99.20000

[ LogP ]:
-1.85

[ 外观性状 ]:
白色至略米色细结晶粉末

[ 蒸汽压 ]:
0.0±1.3 mmHg at 25°C

[ 折射率 ]:
1.596

[ 储存条件 ]:
室温，密封

[ 水溶解性 ]:
6 M NaOH : 50 mg/mL, clear, colorless

乙酸胍MSDS

详细MSDS(安全技术说明书)

乙酸胍安全信息

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
MB7700000

[ 海关编码 ]:
29252000

乙酸胍上下游产品

乙酸胍上游产品

乙酸胍下游产品

乙酸胍制备

由硫脲与溴乙烷反应生成S-乙基硫脲氢溴酸盐，再与甘氨酸反应制得胍乙酸。将硫脲、溴乙烷及无水乙醇混合，于水浴温热3h，使硫脲全部溶解。然后减压蒸出乙醇及过量溴乙烷，使残留物结晶，干燥，得S-乙基硫脲氢溴酸盐。再将氢氧化钠溶液加入所得的S-乙基硫脲氢溴酸盐中，冷却下，迅速加入甘氨酸和水配成的热溶液。结晶后加入乙醚，放置过夜，将混合物在冰浴中冷却2h，分出乙醚层。吸滤，依次用冰水、乙醇、乙醚洗涤，晾干即得成品。

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乙酸胍海关

[ 海关编码 ]: 2925290090

[ 中文概述 ]:
2925290090 其他亚胺及其衍生物，以及它们的盐。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

乙酸胍文献

High-throughput tandem mass spectrometry multiplex analysis for newborn urinary screening of creatine synthesis and transport disorders, Triple H syndrome and OTC deficiency.

Clin. Chim. Acta 436 , 249-55, (2014)

Creatine synthesis and transport disorders, Triple H syndrome and ornithine transcarbamylase deficiency are treatable inborn errors of metabolism. Early screening of patients was found to be beneficia...

Detection of autosomal dominant polycystic kidney disease by NMR spectroscopic fingerprinting of urine.

Kidney Int. 79(11) , 1244-53, (2011)

Autosomal dominant polycystic kidney disease (ADPKD) is a frequent cause of kidney failure; however, urinary biomarkers for the disease are lacking. In a step towards identifying such markers, we used...

Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations.

Kidney Int. 59(6) , 2267-72, (2001)

Hyperhomocysteinemia is a risk factor for atherosclerosis that is common in chronic renal failure (CRF), but its cause is unknown. Homocysteine metabolism is linked to betaine-homocysteine methyl tran...

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乙酸胍