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亚油酸胆固醇酯

亚油酸胆固醇酯用途

Cholesteryl linoleate 是低密度脂蛋白和动脉粥样硬化病变中主要的胆固醇酯。

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亚油酸胆固醇酯名称

[ CAS 号 ]:
604-33-1

[ 中文名 ]:
胆固醇亚油酸酯

[ 英文名 ]:
CHOLESTERYL LINOLEATE

[中文别名 ]:

[英文别名 ]:

Cholesterol Linoleate
Cholesteryl linoleate
EINECS 210-065-9
MFCD00003644

亚油酸胆固醇酯生物活性

[ 描述 ]:

Cholesteryl linoleate 是低密度脂蛋白和动脉粥样硬化病变中主要的胆固醇酯。

[ 相关类别 ]:

研究领域 >> 代谢疾病

天然产物 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Huber J, et al. Oxidized cholesteryl linoleates stimulate endothelial cells to bind monocytes via the extracellular signal-regulated kinase 1/2 pathway. Arterioscler Thromb Vasc Biol. 2002 Apr 1;22(4):581-6.

[相关活性小分子]

亚油酸胆固醇酯物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
677.3±44.0 °C at 760 mmHg

[ 熔点 ]:
42ºC

[ 分子式 ]:
C₄₅H₇₆O₂

[ 分子量 ]:
649.084

[ 闪点 ]:
364.0±16.0 °C

[ 精确质量 ]:
648.584534

[ PSA ]:
26.30000

[ LogP ]:
18.17

[ 外观性状 ]:
白色粉末

[ 蒸汽压 ]:
0.0±2.1 mmHg at 25°C

[ 折射率 ]:
1.517

[ 储存条件 ]:
−20°C

亚油酸胆固醇酯MSDS

亚油酸胆固醇酯安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

亚油酸胆固醇酯合成路线

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亚油酸胆固醇酯文献

Autophagy facilitates secretion and protects against degeneration of the Harderian gland.

Autophagy 11(2) , 298-313, (2015)

The epithelial derived Harderian gland consists of 2 types of secretory cells. The more numerous type A cells are responsible for the secretion of lipid droplets, while type B cells produce dark granu...

A rapid and precise method for quantification of fatty acids in human serum cholesteryl esters by liquid chromatography and tandem mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 960 , 222-9, (2014)

We described a rapid and precise method for simultaneous quantification of eleven fatty acids in human serum cholesteryl esters (CEFAs) by liquid chromatography and tandem mass spectrometry (LC-MS/MS)...

Oxidized cholesteryl linoleates stimulate endothelial cells to bind monocytes via the extracellular signal-regulated kinase 1/2 pathway.

Arterioscler. Thromb. Vasc. Biol. 22(4) , 581-6, (2002)

Oxidation products of cholesteryl esters have been shown to be present in oxidized low density lipoprotein and in atherosclerotic lesions. Monocyte adhesion to the endothelium is an initiating crucial...

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