2,3-二氯-1-丙醇
2,3-二氯-1-丙醇用途
用作硝基喷漆、涂料、清漆用溶剂,赛璐珞黏合剂。也用于制备离子交换树脂等。
2,3-二氯-1-丙醇名称
[ CAS 号 ]:
616-23-9
[ 中文名 ]:
2,3-二氯-1-丙醇
[ 英文名 ]:
UNII:88I7UKE7IM
[中文别名 ]:
[英文别名 ]:
- 2,3-dichloro-1-phenyl-1-propanone
- EINECS 210-470-0
- 2,3-Dichlorpropan-1-ol
- 2,3-Dichloro-1-propanol
- 2,3-Dichloropropan-1-ol
- 2,3-dichloropropane-1-ol
- 1-Propanol, 2,3-dichloro-
- 1-PROPANONE,2,3-DICHLORO-1-PHENYL
- 1,2-dichloro-3-hydroxy propane
- MFCD00040446
2,3-二氯-1-丙醇物理化学性质
[ 密度 ]:
1.3±0.1 g/cm3
[ 沸点 ]:
184.0±0.0 °C at 760 mmHg
[ 分子式 ]:
C3H6Cl2O
[ 分子量 ]:
128.985
[ 闪点 ]:
98.5±15.8 °C
[ 精确质量 ]:
127.979568
[ PSA ]:
20.23000
[ LogP ]:
0.65
[ 外观性状 ]:
透明无色液体
[ 蒸汽压 ]:
0.2±0.7 mmHg at 25°C
[ 折射率 ]:
1.462
[ 储存条件 ]:
室温,干燥
2,3-二氯-1-丙醇MSDS
2,3-二氯-1-丙醇毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UB1225000
- CHEMICAL NAME :
- 1-Propanol, 2,3-dichloro-
- CAS REGISTRY NUMBER :
- 616-23-9
- BEILSTEIN REFERENCE NO. :
- 1732060
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 12
- MOLECULAR FORMULA :
- C3-H6-Cl2-O
- MOLECULAR WEIGHT :
- 128.99
- WISWESSER LINE NOTATION :
- Q1YG1G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Open irritation test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 90 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 ppm/4H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 1 mmol/L
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 9,401,1987
2,3-二氯-1-丙醇安全信息
[ 符号 ]:
GHS05, GHS06
[ 信号词 ]:
Danger
[ 危害声明 ]:
H301-H310-H318-H332
[ 警示性声明 ]:
P280-P302 + P350-P305 + P351 + P338-P310
[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ 危害码 (欧洲) ]:
T:Toxic;
[ 风险声明 (欧洲) ]:
R20;R24/25;R41
[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45
[ 危险品运输编码 ]:
UN 2810 6.1/PG 2
[ WGK德国 ]:
3
[ RTECS号 ]:
UB1225000
[ 包装等级 ]:
III
[ 危险类别 ]:
6.1
2,3-二氯-1-丙醇合成路线
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2,3-二氯-1-丙醇文献
Food Chem. 166 , 301-8, (2014)
Sodium chloride has been shown to promote chlorination of glycerol during thermal processing. However, the detailed mechanism of this reaction is not well understood. Preliminary experiments have indi...
The simultaneous separation and determination of chloropropanols in soy sauce and other flavoring with gas chromatography-mass spectrometry in negative chemical and electron impact ionization modes.Food Addit. Contam. 23(2) , 110-9, (2006)
Both gas chromatography-mass spectrometry in electron ionization (GC-MS-EI) and negative chemical ionization (GC-MS-NCI) modes are reported in this paper for the simultaneous determination of 1,3-dich...
Directed evolution strategies for enantiocomplementary haloalkane dehalogenases: from chemical waste to enantiopure building blocks.ChemBioChem. 13(1) , 137-48, (2012)
We used directed evolution to obtain enantiocomplementary haloalkane dehalogenase variants that convert the toxic waste compound 1,2,3-trichloropropane (TCP) into highly enantioenriched (R)- or (S)-2,...
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