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(s)-3-羟基丁酸

(s)-3-羟基丁酸用途

(S)-3-Hydroxybutanoic acid 是一种正常的人体代谢产物,患有抑郁症的老年患者中升高。在人类中,(S)-3-Hydroxybutanoic acid 在肝脏中由乙酰-CoA 合成,当血糖低时可以被脑用作能量来源。

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(s)-3-羟基丁酸名称

[ CAS 号 ]:
6168-83-8

[ 中文名 ]:
(S)-3-羟基丁酸

[ 英文名 ]:
(S)-3-Hydroxybutanoic acid

[英文别名 ]:

(3S)-3-hydroxybutanoic acid
(S)-3-Hydroxybutanoic acid

(s)-3-羟基丁酸生物活性

[ 描述 ]:

[ 相关类别 ]:

天然产物 >> 酸和醛

研究领域 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[相关活性小分子]

(s)-3-羟基丁酸物理化学性质

[ 密度 ]:
1.195 g/cm3

[ 沸点 ]:
269.2ºC at 760 mmHg

[ 熔点 ]:
45-48ºC

[ 分子式 ]:
C₄H₈O₃

[ 分子量 ]:
104.10500

[ 闪点 ]:
121ºC

[ 精确质量 ]:
104.04700

[ PSA ]:
57.53000

[ 折射率 ]:
1.455

[ 储存条件 ]:
2-8°C

(s)-3-羟基丁酸MSDS

详细MSDS(安全技术说明书)

(s)-3-羟基丁酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
26-36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

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(s)-3-羟基丁酸文献

Thermophilic Coenzyme B12-Dependent Acyl Coenzyme A (CoA) Mutase from Kyrpidia tusciae DSM 2912 Preferentially Catalyzes Isomerization of (R)-3-Hydroxybutyryl-CoA and 2-Hydroxyisobutyryl-CoA.

Appl. Environ. Microbiol. 81 , 4564-72, (2015)

The recent discovery of a coenzyme B12-dependent acyl-coenzyme A (acyl-CoA) mutase isomerizing 3-hydroxybutyryl- and 2-hydroxyisobutyryl-CoA in the mesophilic bacterium Aquincola tertiaricarbonis L108...

Human brain beta-hydroxybutyrate and lactate increase in fasting-induced ketosis.

J. Cereb. Blood Flow Metab. 20(10) , 1502-7, (2000)

Ketones are known to constitute an important fraction of fuel for consumption by the brain, with brain ketone content generally thought to be low. However, the recent observation of 1-mmol/L levels of...

Contribution of 3-hydroxyisobutyrate to the measurement of 3-hydroxybutyrate in human plasma: comparison of enzymatic and gas-liquid chromatography-mass spectrometry assays in normal and in diabetic subjects.

J. Lipid Res. 30(11) , 1811-7, (1989)

In this study we employed a capillary gas-liquid chromatographic-mass spectrometric (GLC-MS) method to measure the plasma concentrations of 3-hydroxybutyrate (3-OHB) and 3-hydroxyisobutyrate (3-OHIB) ...

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