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3-硝基-L-酪氨酸

3-硝基-L-酪氨酸用途

3-Nitro-L-tyrosine 在系统自免疫原性条件下,可作为无氮自由基修饰蛋白的生物标记物。

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3-硝基-L-酪氨酸名称

[ CAS 号 ]:
621-44-3

[ 中文名 ]:
3-硝基-L-酪氨酸

[ 英文名 ]:
3-nitro-L-tyrosine

[中文别名 ]:

[英文别名 ]:

L-3-NO2-Tyr
H-3-NITRO-TYR-OH
M-NITRO-L-TYROSINE
Tyrosine, 3-nitro-, L- (8CI)
EINECS 210-688-6
3-Nitro-Tyrosine
L-Tyrosine, 3-nitro-
Tyrosine, 3-nitro-
Tyrosine, 3-nitro-, L-
3-Nitro-L-tyrosine

3-硝基-L-酪氨酸生物活性

[ 描述 ]:

3-Nitro-L-tyrosine 在系统自免疫原性条件下,可作为无氮自由基修饰蛋白的生物标记物。

[ 相关类别 ]:

研究领域 >> 代谢疾病

天然产物 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Montoliu C, et al. 3-nitro-tyrosine as a peripheral biomarker of minimal hepatic encephalopathy in patients with liver cirrhosis. Am J Gastroenterol. 2011 Sep;106(9):1629-37.

[相关活性小分子]

3-硝基-L-酪氨酸物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
431.6±45.0 °C at 760 mmHg

[ 熔点 ]:
233-235ºC (dec.)

[ 分子式 ]:
C₉H₁₀N₂O₅

[ 分子量 ]:
226.186

[ 闪点 ]:
214.8±28.7 °C

[ 精确质量 ]:
226.058975

[ PSA ]:
129.37000

[ LogP ]:
0.60

[ 外观性状 ]:
黄色至绿色粉末

[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C

[ 折射率 ]:
1.651

[ 储存条件 ]:
2~8℃

3-硝基-L-酪氨酸MSDS

3-硝基-L-酪氨酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2922509090

3-硝基-L-酪氨酸合成路线

3-硝基-L-酪氨酸上下游产品

3-硝基-L-酪氨酸上游产品

3-硝基-L-酪氨酸下游产品

3-硝基-L-酪氨酸海关

[ 海关编码 ]: 2922509090

[ 中文概述 ]:
2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

3-硝基-L-酪氨酸文献

Interferon-gamma induced cell death: Regulation and contributions of nitric oxide, cJun N-terminal kinase, reactive oxygen species and peroxynitrite.

Biochim. Biophys. Acta 1843(11) , 2645-61, (2014)

Interferon-gamma (Ifnγ), a known immunomodulatory cytokine, regulates cell proliferation and survival. In this study, the mechanisms leading to the selective susceptibility of some tumor cells to Ifnγ...

Early redox imbalance is associated with liver dysfunction at weaning in overfed rats.

J. Physiol. 593 , 4799-811, (2015)

Neonatal overfeeding induced by litter size reduction leads to further obesity and other metabolic disorders, such as liver oxidative stress and microsteatosis at adulthood. We hypothesized that overf...

Epithelial MUC1 promotes cell migration, reduces apoptosis and affects levels of mucosal modulators during acetylsalicylic acid (aspirin)-induced gastropathy.

Biochem. J. 465(3) , 423-31, (2015)

MUC1 is a transmembrane mucin highly expressed in the stomach. Although extensive research has uncovered many of its roles in cancer, knowledge about the functions of MUC1 in normal tissues is limited...

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