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N-反式阿魏酰酪胺

N-反式阿魏酰酪胺用途

N-trans-Feruloyltyramine (N-feruloyltyramine) 是从Piper nigru 中分离得到的一种生物碱,是COX1 和COX2 的抑制剂,具有抗氧化和抗炎活性。

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N-反式阿魏酰酪胺名称

[ CAS 号 ]:
66648-43-9

[ 中文名 ]:
N-反式-阿魏酰酪胺

[ 英文名 ]:
N-trans-Feruloyltyramine

[中文别名 ]:

N-反式阿魏酰酪胺

[英文别名 ]:

6,7-dimethoxy-5-hydroxyflavone
5-Hydroxy-6,7-dimethoxy-2-phenyl-4H-chromen-4-one
N-trans-Feruloyltyramine
5-Hydroxy-6,7-dimethoxyflavone
6,7-di-O-methyl-baicalein
moupinamide
baicalein 6,7-dimethyl ether
Mosloflavone

N-反式阿魏酰酪胺生物活性

[ 描述 ]:

N-trans-Feruloyltyramine (N-feruloyltyramine) 是从Piper nigru 中分离得到的一种生物碱,是COX1 和COX2 的抑制剂,具有抗氧化和抗炎活性。

[ 相关类别 ]:

研究领域 >> 炎症/免疫

信号通路 >> 免疫及炎症 >> COX

[ 靶点 ]

COX-1

COX-2

[参考文献]

[1]. Aswad M, et al. Nature is the best source of anti-inflammatory drugs: indexing natural products for their anti-inflammatory bioactivity. Inflamm Res. 2018 Jan;67(1):67-75.

N-反式阿魏酰酪胺物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
554.2±60.0 °C at 760 mmHg

[ 分子式 ]:
C₁₈H₁₉NO₄

[ 分子量 ]:
313.348

[ 闪点 ]:
289.0±32.9 °C

[ 精确质量 ]:
313.131409

[ PSA ]:
78.79000

[ LogP ]:
3.33

[ 外观性状 ]:
粉末

[ 蒸汽压 ]:
0.0±1.6 mmHg at 25°C

[ 折射率 ]:
1.566

[ 储存条件 ]:
?20°C

N-反式阿魏酰酪胺MSDS

详细MSDS(安全技术说明书)

N-反式阿魏酰酪胺安全信息

[ 符号 ]:

GHS09

[ 信号词 ]:
Warning

[ 危害声明 ]:
H410

[ 警示性声明 ]:
P273-P501

[ 危害码 (欧洲) ]:
N

[ 风险声明 (欧洲) ]:
50

[ 安全声明 (欧洲) ]:
61

[ 危险品运输编码 ]:
UN 3077 9 / PGIII

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N-反式阿魏酰酪胺文献

Transgenic tomato plants overexpressing tyramine N-hydroxycinnamoyltransferase exhibit elevated hydroxycinnamic acid amide levels and enhanced resistance to Pseudomonas syringae.

Mol. Plant Microbe Interact. 27(10) , 1159-69, (2014)

Hydroxycinnamic acid amides (HCAA) are secondary metabolites involved in plant development and defense that have been widely reported throughout the plant kingdom. These phenolics show antioxidant, an...

A feruloyltyramine trimer isolated from potato common scab lesions

Phytochemistry 71(17-18) , 2187-9, (2010)

Graphical abstract A lignanamide isolated from potato common scab lesions was characterized as a feruloyltyramine trimer by MS and NMR techniques.

Endosperm-specific expression of serotonin N-hydroxycinnamoyltransferase in rice.

Plant Foods Hum. Nutr. 63(2) , 53-7, (2008)

Serotonin N-hydroxycinnamoyltransferase (SHT) is a key enzyme in the synthesis of feruloylserotonin (FS) and 4-coumaroylserotonin (CS). These serotonin derivatives show strong antioxidant activity, ma...

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