2'-羟基-4'-甲基苯乙酮

2'-羟基-4'-甲基苯乙酮用途

2'-Hydroxy-4'-methylacetophenone 是从韩国当归 (Angelicae koreana) 的根部分离出来的酚类化合物,具有杀螨活性[1],可用于合成 4’-methyl-2’-[(p-tolylsulfonyl) oxy] acetophenone[2]。

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2'-羟基-4'-甲基苯乙酮名称

[ CAS 号 ]:
6921-64-8

[ 中文名 ]:
2′-羟基-4′-甲基苯乙酮

[ 英文名 ]:
2'-Hydroxy-4'-methylacetophenone

[中文别名 ]:

[英文别名 ]:

EINECS 230-040-6
1-(2-hydroxy-4-methylphenyl)ethanone
MFCD00100559
2'-Hydroxy-4'-methylacetophenone

2'-羟基-4'-甲基苯乙酮生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 其他

天然产物 >> 酚类

[参考文献]

[1]. Oh MS, et al. Acaricidal toxicity of 2'-hydroxy-4'-methylacetophenone isolated from Angelicae koreana roots and structure-activity relationships of its derivatives. J Agric Food Chem. 2012 Apr 11;60(14):3606-11.

[2]. De Meyer N, et al. 4'-Hydroxy-3-methoxyflavones with potent antipicornavirus activity. J Med Chem. 1991 Feb;34(2):736-46.

[相关活性小分子]

2'-羟基-4'-甲基苯乙酮物理化学性质

[ 密度 ]:
1.08 g/mL at 25 °C(lit.)

[ 沸点 ]:
245 °C(lit.)

[ 熔点 ]:
45-48ºC

[ 分子式 ]:
C₉H₁₀O₂

[ 分子量 ]:
150.17400

[ 闪点 ]:
>230 °F

[ 精确质量 ]:
150.06800

[ PSA ]:
37.30000

[ LogP ]:
1.90320

[ 外观性状 ]:
黑色液体

[ 折射率 ]:
n20/D 1.565(lit.)

[ 储存条件 ]:
室温

2'-羟基-4'-甲基苯乙酮MSDS

详细MSDS(安全技术说明书)

2'-羟基-4'-甲基苯乙酮安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2914501900

2'-羟基-4'-甲基苯乙酮合成路线

详细合成路线

2'-羟基-4'-甲基苯乙酮海关

[ 海关编码 ]: 2914501900

[ 中文概述 ]:
2914501900 其他酮酚。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 丙酮报明包装

[ Summary ]:
2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

2'-羟基-4'-甲基苯乙酮文献

Acaricidal toxicity of 2'-hydroxy-4'-methylacetophenone isolated from Angelicae koreana roots and structure-activity relationships of its derivatives.

J. Agric. Food Chem. 60(14) , 3606-11, (2012)

The acaricidal activities of 2'-hydroxy-4'-methylacetophenone derived from Angelica koreana roots and its derivatives against Dermatophagoides farinae, Dermatophagoides pteronyssinus, and Tyrophagus p...

Zirconium tetrachloride as a mediator for ambient temperature ortho-fries rearrangements. Harrowven DC and Dainty RF.

Tetrahedron 37(42) , 7659-7660, (1996)

4'-Hydroxy-3-methoxyflavones with potent antipicornavirus activity. De Meyer N, et al.

J. Med. Chem. 34(2) , 736-746, (1991)

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