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3,3'-二氨基联苯胺四盐酸盐

3,3'-二氨基联苯胺四盐酸盐用途

3,3'-Diaminobenzidine(DAB)是有机化合物,具有化学和热力学稳定性,可用于核酸和蛋白的免疫组化染色。

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3,3'-二氨基联苯胺四盐酸盐名称

[ CAS 号 ]:
7411-49-6

[ 中文名 ]:
3,3'-二氨基联苯胺四盐酸盐

[ 英文名 ]:
3,3',4,4'-Biphenyltetramine tetrahydrochloride

[中文别名 ]:

[英文别名 ]:

DAB TABLET
DAB SUBSTRATE
DAB-HCL
Biphenyl-3,3',4,4'-tetramine tetrahydrochloride
DAB TETRAHYDROCHLORIDE
DAB
3,3',4,4'-Biphenyltetramine tetrahydrochloride
DAB,tetrahydrochloride3
3,3`-Diaminobenzidine tetrahydrochloride
DAB EASY tablets

3,3'-二氨基联苯胺四盐酸盐生物活性

[ 描述 ]:

3,3'-Diaminobenzidine(DAB)是有机化合物,具有化学和热力学稳定性,可用于核酸和蛋白的免疫组化染色。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

染料试剂

研究领域 >> 其他

[参考文献]

[1]. Hannetz Roschzttardtz, et al. Plant Cell Nucleolus as a Hot Spot for Iron.

[相关活性小分子]

3,3'-二氨基联苯胺四盐酸盐物理化学性质

[ 沸点 ]:
481.7ºC at 760 mmHg

[ 熔点 ]:
300°C

[ 分子式 ]:
C₁₂H₁₈Cl₄N₄

[ 分子量 ]:
360.110

[ 闪点 ]:
282.7ºC

[ 精确质量 ]:
358.028564

[ PSA ]:
104.08000

[ LogP ]:
7.21520

[ 外观性状 ]:
灰色至紫色-棕色粉末

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开存放

[ 水溶解性 ]:
Soluble

3,3'-二氨基联苯胺四盐酸盐MSDS

详细MSDS(安全技术说明书)

3,3'-二氨基联苯胺四盐酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DV8753000

CHEMICAL NAME :: 3,3',4,4'-Biphenyltetramine, tetrahydrochloride

CAS REGISTRY NUMBER :: 7411-49-6

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C12-H14-N4.4Cl-H

MOLECULAR WEIGHT :: 360.14

WISWESSER LINE NOTATION :: ZR BZ DR CZ DZ &GH 4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 330 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NCIBR* Progress Report for Contract No. NIH-NCI-E-68-1311, Submitted to the National Cancer Institute by Bio-Research Consultants, Inc. (9 Commercial Ave., Cambridge, MA 02141) Volume(issue)/page/year: NCI-E-68-1311,1973 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 260 gm/kg/78W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors

REFERENCE :: JEPTDQ Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC. Volume(issue)/page/year: 2(2),325,1978

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 260 gm/kg/78W-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors

REFERENCE :: JEPTDQ Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC. Volume(issue)/page/year: 2(2),325,1978

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 520 gm/kg/78W-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors

REFERENCE :: JEPTDQ Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC. Volume(issue)/page/year: 2(2),325,1978

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3,3'-二氨基联苯胺四盐酸盐安全信息

[ 符号 ]:

GHS07, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302-H319-H341-H350

[ 警示性声明 ]:
P201-P280-P301 + P312 + P330-P305 + P351 + P338-P308 + P313-P337 + P313

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R22;R36/37/38;R40

[ 安全声明 (欧洲) ]:
S7-S16-S24-S33-S36/37-S45-S24/25-S22

[ 危险品运输编码 ]:
UN 3316 9/PG 2

[ WGK德国 ]:
3

[ RTECS号 ]:
DV8753000

[ 危险类别 ]:
9.0

3,3'-二氨基联苯胺四盐酸盐文献

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Bull. Environ. Contam. Toxicol. 87(3) , 226-30, (2011)

The objective of this study was to examine the influence of different stressors, including cadmium (heavy metal), anthracene (polycyclic aromatic hydrocarbon-PAH) and chloridazon (herbicide), on popul...

The bioanalysis of trastuzumab in human serum using precipitate-enhanced ellipsometry.

Anal. Biochem. 393 , 73-79, (2009)

For the bioanalysis of therapeutic monoclonal antibodies in biological matrices, immunoassays--especially enzyme-linked immunosorbent assays (ELISAs)--are the most widely used techniques. Although ELI...

Color modification of diaminobenzidine (DAB) precipitation by metallic ions and its application for double immunohistochemistry.

J. Histochem. Cytochem. 30 , 1079-1082, (1982)

Three metallic ions, NiCl2, CoCl2, and CuSO4, were found to modify the color of the normally brown diaminobenzidine (DAB) reaction. The colors ranged from purplish blue (NiCl2), dark blue/bluish black...

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