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3-氯-L-酪氨酸

3-氯-L-酪氨酸用途

3-Chloro-L-tyrosine 是髓过氧化物酶催化氧化中的特异性标记,在人类动脉粥样硬化内膜分离出的低密度脂蛋白中明显升高。

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3-氯-L-酪氨酸名称

[ CAS 号 ]:
7423-93-0

[ 中文名 ]:
3-氯-L-酪氨酸

[ 英文名 ]:
3-Chloro-L-tyrosine

[英文别名 ]:

3-Chlorophenetole
3-chloro-l(-)-tyrosine
m-chloro-L-tyrosine
Phenetole,m-chloro
3-Chlor-phenetol
m-chloroethoxybenzene
Tyrosine, 3-chloro-
L-3-chlorotyrosine
3-chlorophenetol
Benzene,1-chloro-3-ethoxy

3-氯-L-酪氨酸生物活性

[ 描述 ]:

3-Chloro-L-tyrosine 是髓过氧化物酶催化氧化中的特异性标记,在人类动脉粥样硬化内膜分离出的低密度脂蛋白中明显升高。

[ 相关类别 ]:

天然产物 >> 其他

研究领域 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Hazen SL, et al. 3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima. J Clin Invest. 1997 May 1;99(9):2075-81.

[相关活性小分子]

3-氯-L-酪氨酸物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
388.6±42.0 °C at 760 mmHg

[ 熔点 ]:
249ºC

[ 分子式 ]:
C₉H₁₀ClNO₃

[ 分子量 ]:
215.634

[ 闪点 ]:
188.8±27.9 °C

[ 精确质量 ]:
215.034927

[ PSA ]:
83.55000

[ LogP ]:
0.93

[ 外观性状 ]:
白色粉末

[ 蒸汽压 ]:
0.0±0.9 mmHg at 25°C

[ 折射率 ]:
1.625

[ 储存条件 ]:
室温，干燥

3-氯-L-酪氨酸MSDS

3-氯-L-酪氨酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2922509090

3-氯-L-酪氨酸合成路线

3-氯-L-酪氨酸上下游产品

3-氯-L-酪氨酸上游产品

3-氯-L-酪氨酸下游产品

3-氯-L-酪氨酸海关

[ 海关编码 ]: 2922509090

[ 中文概述 ]:
2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

3-氯-L-酪氨酸文献

Serum and adipose tissue amino acid homeostasis in the metabolically healthy obese.

J. Proteome Res. 13(7) , 3455-66, (2014)

A subgroup of obese individuals, referred to as metabolically healthy obese (MHO), have preserved insulin sensitivity and a normal lipid profile despite being obese. The molecular basis for this impro...

Protein stabilization utilizing a redefined codon.

Sci. Rep. 5 , 9762, (2015)

Recent advances have fundamentally changed the ways in which synthetic amino acids are incorporated into proteins, enabling their efficient and multiple-site incorporation, in addition to the 20 canon...

Syntheses of halogen derivatives of L-tryptophan, L-tyrosine and L-phenylalanine labeled with hydrogen isotopes.

J. Labelled Comp. Radiopharm. 59 , 08-Apr, (2016)

Halogenated, labeled with tritium and doubly with deuterium and tritium, derivatives of L-tryptophan, i.e. 5'-bromo-[2-(3)H]-, 5'-bromo-[2-(2)H/(3)H]-, 5'-fluoro-[2-(3)H]-5'-fluoro-[2-(2)H/(3)H]-, 6'-...

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