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顺式-4,7,10,13,16,19-二十二碳六烯酸乙酯

顺式-4,7,10,13,16,19-二十二碳六烯酸乙酯用途

Ethyl cis-4,7,10,13,16,19-Docosahexaenoate 是二十二碳六烯酸 (DHA) 的乙酯,是金枪鱼油和月桂醇反应中提出的醇化脂肪酸乙酯。

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顺式-4,7,10,13,16,19-二十二碳六烯酸乙酯名称

[ CAS 号 ]:
84494-72-4

[ 中文名 ]:
顺-4,7,10,13,16,19-二十二碳六烯酸乙酯

[ 英文名 ]:
cis-4,7,10,13,16,19-Docosahexaenoic acid ethyl ester

[中文别名 ]:

DHA乙酯

[英文别名 ]:

MFCD00056293
4,7,10,13,16,19-docosahexaenoic acid ethyl ester
4,7,10,13,16,19-Docosahexaenoic acid, ethyl ester

顺式-4,7,10,13,16,19-二十二碳六烯酸乙酯生物活性

[ 描述 ]:

Ethyl cis-4,7,10,13,16,19-Docosahexaenoate 是二十二碳六烯酸 (DHA) 的乙酯,是金枪鱼油和月桂醇反应中提出的醇化脂肪酸乙酯。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 代谢疾病

[体外研究]

顺式-4,7,10,13,16,19-二十二碳六烯酸乙酯(二十二碳六烯酸乙酯; E-DHA)通过使用固定化脂肪酶[1]选择性醇解来自金枪鱼油的月桂醇的乙醇酯而得到有效富集[1]。

[参考文献]

[1]. Yuji Shimada, et al. Purification of ethyl docosahexaenoate by selective alcoholysis of fatty acid ethyl esters with immobilized Rhizomucor miehei lipase. J Am Oil Chem Soc. 1998 Nov, 75(11): 1565–1571.

[相关活性小分子]

顺式-4,7,10,13,16,19-二十二碳六烯酸乙酯物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
443.5±24.0 °C at 760 mmHg

[ 分子式 ]:
C₂₄H₃₆O₂

[ 分子量 ]:
356.541

[ 闪点 ]:
102.1±21.2 °C

[ 精确质量 ]:
356.271515

[ PSA ]:
26.30000

[ LogP ]:
7.77

[ 外观性状 ]:
液体;Colorless to Light yellow to Light orange clear liquid

[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C

[ 折射率 ]:
1.504

[ 储存条件 ]:
−20°C

顺式-4,7,10,13,16,19-二十二碳六烯酸乙酯MSDS

详细MSDS(安全技术说明书)

顺式-4,7,10,13,16,19-二十二碳六烯酸乙酯安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

顺式-4,7,10,13,16,19-二十二碳六烯酸乙酯文献

Docosahexaenoic acid counteracts attenuation of CD95-induced cell death by inorganic mercury.

Toxicol. Appl. Pharmacol. 282(1) , 61-7, (2015)

In the United States the principal environmental exposure to mercury is through dietary consumption of sea food. Although the mechanism by which low levels of mercury affect the nervous system is not ...

Protective effects of prescription n-3 fatty acids against impairment of spatial cognitive learning ability in amyloid β-infused rats.

Food Funct. 2(7) , 386-94, (2011)

Deposition of amyloid β peptide (Aβ) into the brain causes cognitive impairment. We investigated whether prescription pre-administration of n-3 fatty acids improves cognitive learning ability in young...

Identification of inflammatory and proresolving lipid mediators in bone marrow and their lipidomic profiles with ovariectomy and omega-3 intake.

Am. J. Hematol. 83(6) , 437-45, (2008)

Newly described lipoxygenase (LOX)-generated lipid mediators, that is, resolvins and protectins as well as lipoxins, are both anti-inflammatory and proresolving. We aimed to determine whether these li...

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